Erectile Dysfunction, Testosterone Levels and Disease Activity in Ankylosing Spondylitis Patients

Erectile Dysfunction, Testosterone Levels and Disease Activity in Ankylosing Spondylitis Patients

To study erectile function in male patients with Ankylosing Spondylitis (AS) trying to correlate it with sexual hormonal profile and disease activity. We included 35 AS patients and 104 controls. Patients and controls answered the IIEF (International Index of Erectile Dysfunction) and had dosing of...

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Veröffentlicht in:Urology (Ridgewood, N.J.) N.J.), 2021-07, Vol.153, p.210-214
Hauptverfasser: Nisihara, Renato, Heil Junior, LJ, Fagundes, Felipe Guzzo, Sobreiro, Bernardo, Campos, Ana P.B., Simioni, Juliana, Skare, Thelma L.
Format: Artikel
Sprache:eng
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Adult
Aged
Correlation of Data
Cross-Sectional Studies
Erectile Dysfunction - blood
Erectile Dysfunction - etiology
Humans
Male
Middle Aged
Spondylitis, Ankylosing - blood
Spondylitis, Ankylosing - complications
Testosterone - blood
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container_end_page 214
container_issue
container_start_page 210
container_title Urology (Ridgewood, N.J.)
container_volume 153
creator Nisihara, Renato
Heil Junior, LJ
Fagundes, Felipe Guzzo
Sobreiro, Bernardo
Campos, Ana P.B.
Simioni, Juliana
Skare, Thelma L.
description To study erectile function in male patients with Ankylosing Spondylitis (AS) trying to correlate it with sexual hormonal profile and disease activity. We included 35 AS patients and 104 controls. Patients and controls answered the IIEF (International Index of Erectile Dysfunction) and had dosing of total testosterone, free testosterone (FT), bioavailable testosterone (BT), SHBG (serum hormone binding globulin), albumin and LH (luteinizing hormone). AS patients had epidemiological, clinical and treatment data obtained from the charts. AS disease activity was measured simultaneously with blood collection through Bath AS Disease Activity Index, ASDAS (AS Disease Activity Score) -ESR (using erythrocyte sedimentation rate) and ASDAS-CRP (using C reactive protein). The IIEF results were worse in AS patients than controls (P = .02). Total testosterone and SHBG were higher in AS (with P = .01 and P
doi_str_mv 10.1016/j.urology.2021.01.008
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In AS patients, the IIEF results did not correlate with total testosterone, SHBG, LH, FT, and BT but a negative association was found with Bath AS Disease Activity Index (P = .001) and ASDAS-CRP (P = .02). 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source MEDLINE; ScienceDirect Journals (5 years ago - present)
subjects Adult
Aged
Correlation of Data
Cross-Sectional Studies
Erectile Dysfunction - blood
Erectile Dysfunction - etiology
Humans
Male
Middle Aged
Spondylitis, Ankylosing - blood
Spondylitis, Ankylosing - complications
Testosterone - blood
title Erectile Dysfunction, Testosterone Levels and Disease Activity in Ankylosing Spondylitis Patients
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