Mode and dynamics of vanA-type vancomycin resistance dissemination in Dutch hospitals

Background Enterococcus faecium is a commensal of the gastrointestinal tract of animals and humans but also a causative agent of hospital-acquired infections. Resistance against glycopeptides and to vancomycin has motivated the inclusion of E. faecium in the WHO global priority list. Vancomycin resi...

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Veröffentlicht in:	Genome medicine 2021-01, Vol.13 (1), p.9-9, Article 9
Hauptverfasser:	Arredondo-Alonso, Sergio, Top, Janetta, Corander, Jukka, Willems, Rob J. L., Schurch, Anita C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Antibiotics Bacterial Proteins - metabolism Base Sequence Clonal dissemination Drug resistance in microorganisms Enterococcus faecium Enterococcus faecium - genetics Enterococcus faecium - physiology Epidemiology Feasibility studies Gastrointestinal system Gastrointestinal tract Gene transfer Genes Genetics & Heredity Genome sequencing Genomes Genomics Glycopeptides Gram-Positive Bacterial Infections - microbiology Gram-Positive Bacterial Infections - transmission Health aspects Horizontal dissemination Horizontal transfer Hospitals Humans Infection Infections Life Sciences & Biomedicine Netherlands - epidemiology Network Plasmids Plasmids - genetics Reproducibility of Results Science & Technology Time Factors Transposition Transposon Tn1546 Transposons VanA gene Vancomycin Vancomycin Resistance Vancomycin-Resistant Enterococci - genetics Vancomycin-Resistant Enterococci - isolation & purification
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