Robustness and timing of cellular differentiation through population-based symmetry breaking

During mammalian development and homeostasis, cells often transition from a multilineage primed state to one of several differentiated cell types that are marked by the expression of mutually exclusive genetic markers. These observations have been classically explained by single-cell multistability...

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Veröffentlicht in:Development (Cambridge) 2021-02, Vol.148 (3)
Hauptverfasser: Stanoev, Angel, Schröter, Christian, Koseska, Aneta
Format: Artikel
Sprache:eng
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