The histone deacetylase inhibitor, entinostat (MS-275), induces the odontogenic differentiation of an odontoblast-like cell line in the absence of an osteoblast mineralization medium

[Abstract] The aim of this study was to determine whether histone deacetylase inhibitors (HDACi), including entinostat (MS-275), valproic acid (VPA), trichostatin A (TSA), and sodium butyrate (NaB), promoted the odontogenic differentiation of the odontoblast-like cell line, MDPC-23 in the absence of...

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Veröffentlicht in:	Odontology 2021-07, Vol.109 (3), p.661-671
Hauptverfasser:	Sultana, Shamima, Uehara, Osamu, Yoshida, Koki, Saito, Takashi, Abiko, Yoshihiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkaline phosphatase Bone healing Bone morphogenetic protein 2 Bone morphogenetic proteins Cbfa-1 protein Cell culture Cell differentiation Cell migration Cell proliferation Collagen Dental pulp Dentistry Dmp1 protein Dspp protein Gene expression Histone deacetylase Homeobox Krueppel-like factor Medicine Mineralization Oral and Maxillofacial Surgery Original Article Osteoblastogenesis Osteoblasts Osteocalcin Polymerase chain reaction Sodium butyrate Trichostatin A Wound healing
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