Selective inhibition of acylpeptide hydrolase in SAOS-2 osteosarcoma cells: is this enzyme a viable anticancer target?

Serine hydrolases play crucial roles in many physiological and pathophysiological processes and a panel of these enzymes are targets of approved drugs. Despite this, most of the human serine hydrolases remain poorly characterized with respect to their biological functions and substrates and only a l...

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Veröffentlicht in:Molecular biology reports 2021-02, Vol.48 (2), p.1505-1519
Hauptverfasser: Gogliettino, Marta, Cocca, Ennio, Sandomenico, Annamaria, Gratino, Lorena, Iaccarino, Emanuela, Calvanese, Luisa, Rossi, Mosè, Palmieri, Gianna
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Sprache:eng
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