Frontline Science: Characterization and regulation of osteoclast precursors following chronic Porphyromonas gingivalis infection

Bone destruction in inflammatory osteolytic diseases including periodontitis is related to excessive activity of osteoclasts (OC), which originate from precursor cells of the myeloid lineage, termed osteoclast precursors (OCP). In contrast to ample knowledge that we currently have on mature OC, litt...

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Veröffentlicht in:	Journal of leukocyte biology 2020-10, Vol.108 (4), p.1037-1050
Hauptverfasser:	Zhao, Yanfang, Li, Zhaofei, Su, Lingkai, Ballesteros‐Tato, Andre, Katz, Jannet, Michalek, Suzanne M, Feng, Xu, Zhang, Ping
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bacteroidaceae Infections - genetics Bacteroidaceae Infections - immunology Bacteroidaceae Infections - pathology Bone Resorption - genetics Bone Resorption - immunology Bone Resorption - microbiology Bone Resorption - pathology Chronic Disease Disease Models, Animal Mice Mice, Knockout osteoclast precursors osteoclastogenesis osteoclasts Osteoclasts - immunology Osteoclasts - pathology Porphyromonas gingivalis Porphyromonas gingivalis - immunology RNA-Seq Stem Cells - immunology Stem Cells - pathology
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