Long-term plasmapheresis therapy in the management of focal segmental glomerulosclerosis recurrence after kidney transplantation
The recurrence of primary focal segmental glomerulosclerosis (FSGS) after kidney transplantation (KT) appears in 30 % of the recipients. Sometimes it can cause the loss of the allograft. Although many treatments for this condition have been reported, 20 %–40 % of the affected patients are refractory...
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Veröffentlicht in: | Transfusion and apheresis science 2021-04, Vol.60 (2), p.103046-103046, Article 103046 |
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creator | Ramirez-Guerrero, Gonzalo Sevillano Prieto, Angel M Jara-Vilugrón, Fernando Polanco Fernandez, Natalia Gonzalez Monte, Esther Henandez Vicente, Ana Rodriguez Gayo, Lucia C Praga Terente, Manuel Andrés Belmonte, Amado |
description | The recurrence of primary focal segmental glomerulosclerosis (FSGS) after kidney transplantation (KT) appears in 30 % of the recipients. Sometimes it can cause the loss of the allograft. Although many treatments for this condition have been reported, 20 %–40 % of the affected patients are refractory or presents frequents relapses. In this paper we describe the evolution of three recipients treated with long-term plasmapheresis therapy after a recurrence of FSGS with a bad or incomplete response to other treatments. Although our findings require confirmation, long-term plasmapheresis could be a therapeutic option for this condition. |
doi_str_mv | 10.1016/j.transci.2020.103046 |
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subjects | Focal segmental glomerulosclerosis Health technology assessment Kidney transplantation Plasmapheresis |
title | Long-term plasmapheresis therapy in the management of focal segmental glomerulosclerosis recurrence after kidney transplantation |
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