Three-Dimensional Spheroid Culture on Polymer-Coated Surface Potentiate Stem Cell Functions via Enhanced Cell–Extracellular Matrix Interactions

The aggregation of mesenchymal stem cells (MSCs) into three-dimensional (3D) spheroids has emerged as a promising therapeutic candidate for the treatment of a variety of diseases. In spite of the numerous 3D culture methods suggested recently for MSC spheroid generation, it is still elusive to fully...

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Veröffentlicht in:	ACS biomaterials science & engineering 2020-04, Vol.6 (4), p.2240-2250
Hauptverfasser:	Yu, Seung Jung, Choi, Goro, Cho, Youngbin, Lee, Minseok, Cho, Younghak, Shin, Jennifer H, Lee, Eunjung, Im, Sung Gap
Format:	Artikel
Sprache:	eng
Schlagworte:	Extracellular Matrix Humans Mechanotransduction, Cellular Polymers Spheroids, Cellular Stem Cells
Online-Zugang:	Volltext
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