Icarisid II promotes proliferation and neuronal differentiation of neural stem cells via activating Wnt/β‐catenin signaling pathway

Adult neurogenesis plays a vital role in maintaining cognitive functions in mammals and human beings. Mobilization of hippocampal neurogenesis has been regarded as a promising therapeutic approach to restore injured neurons in neurodegenerative diseases including Alzheimer's disease (AD). Icari...

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Veröffentlicht in:	Phytotherapy research 2021-05, Vol.35 (5), p.2773-2784
Hauptverfasser:	Xiao, Hong‐He, Zhang, Ming‐Bo, Xu, Jun‐Ting, Deng, Yan, Li, Ning, Gao, Peng, Li, Yan, Kong, Liang, Li, Wan‐yi, Chen, Ji‐Cong, Li, Hong‐Yan, Shan, Guo‐Shun, Tai, He, Yang, Jing‐Xian
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer's disease Amyloid Apoptosis Astrocytes Catenin Cell differentiation Cell proliferation Cognitive ability Differentiation Glycogen Glycogen synthase kinase 3 Glycogens Hippocampus icarisid II Kinases neural stem cell Neural stem cells Neurodegenerative diseases Neurogenesis Neuroprotection Nuclear transfer Phosphorylation proliferation Signal transduction Signaling Stem cells Wnt protein Wnt/β‐catenin signaling pathway
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