HLA association with the susceptibility to anti-synthetase syndrome

•HLA typing may help to identify patients with ASSD.•HLA-DRB1*03:01 and HLA-B1*08:01 are predisposition markers of ASSD.•HLA-DRB1*07:01 is a protective allele against ASSD.•HLA-DRB1*03:01 increases the risk of developing anti-Jo-1 autoantibodies in ASSD.•Smoking does not seem to influence anti-Jo-1...

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Veröffentlicht in:	Joint, bone, spine : revue du rhumatisme bone, spine : revue du rhumatisme, 2021-05, Vol.88 (3), p.105115-105115, Article 105115
Hauptverfasser:	Remuzgo-Martínez, Sara, Atienza-Mateo, Belén, Ocejo-Vinyals, J. Gonzalo, Pulito-Cueto, Verónica, Prieto-Peña, Diana, Genre, Fernanda, Marquez, Ana, Llorca, Javier, Mora Cuesta, Víctor M., Fernández, David Iturbe, Riesco, Laura, Ortego-Centeno, Norberto, Gómez, Nair Pérez, Mera, Antonio, Martínez-Barrio, Julia, López-Longo, Francisco Javier, Lera-Gómez, Leticia, Moriano, Clara, Díez, Elvira, Tomero, Eva, Calvo-Alén, Jaime, Romero-Bueno, Fredeswinda, Sanchez-Pernaute, Olga, Nuño, Laura, Bonilla, Gema, Grafia, Ignacio, Prieto-González, Sergio, Narvaez, Javier, Trallero-Araguas, Ernesto, Selva-O’Callaghan, Albert, Gualillo, Oreste, Martín, Javier, Cavagna, Lorenzo, Castañeda, Santos, Cifrian, José M., Renzoni, Elisabetta A., López-Mejías, Raquel, González-Gay, Miguel A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Anti-Jo-1 antibodies Anti-synthetase syndrome Antibodies, Antinuclear Autoantibodies Case-Control Studies Genetic Predisposition to Disease HLA HLA Antigens HLA-B08:01 HLA-DRB1 Chains - genetics HLA-DRB103:01 HLA-DRB107:01 Humans Ligases Myositis - genetics
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