IgG4-related disease manifesting as symptoms of appendicitis: Case report and literature review
Immunoglobulin G subclass 4 (IgG4)-related disease is a recently described fibroinflammatory condition. Reports of appendix involvement are extremely limited. A young man with abdominal pain and symptoms of acute appendicitis accompanied by the finding of an appendix-dependent tumor during surgery i...
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Veröffentlicht in: | Clinical journal of gastroenterology 2021-04, Vol.14 (2), p.626-632 |
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creator | Cabrales-Escobar, Iván Eduardo Murcio-Pérez, Enrique Albarrán-Sánchez, Alejandra |
description | Immunoglobulin G subclass 4 (IgG4)-related disease is a recently described fibroinflammatory condition. Reports of appendix involvement are extremely limited. A young man with abdominal pain and symptoms of acute appendicitis accompanied by the finding of an appendix-dependent tumor during surgery is presented. Histopathological study revealed lymphoplasmocytic infiltrate, storiform fibrosis and obliterative phlebitis. The number of IgG4-positive plasma cells was greater than 50 per high power field. Postsurgical steroid treatment and radiological findings are also described. |
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Reports of appendix involvement are extremely limited. A young man with abdominal pain and symptoms of acute appendicitis accompanied by the finding of an appendix-dependent tumor during surgery is presented. Histopathological study revealed lymphoplasmocytic infiltrate, storiform fibrosis and obliterative phlebitis. The number of IgG4-positive plasma cells was greater than 50 per high power field. Postsurgical steroid treatment and radiological findings are also described.</description><subject>Abdominal Surgery</subject><subject>Case Report</subject><subject>Colorectal Surgery</subject><subject>Gastroenterology</subject><subject>Hepatology</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Surgical Oncology</subject><issn>1865-7257</issn><issn>1865-7265</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNp9kE9PwzAMxSMEYjD4AhxQjlwCTtI2KTc0wZg0iQuco7R1p0z9R9KC9u3p6NiRky37vSf7R8gNh3sOoB4CF1JoBgIYcCkV0yfkguskZkok8emxj9WMXIawBUgEKHlOZlJGCQBPL4hZbZYR81jZHgtauIA2IK1t40oMvWs21AYadnXXt3WgbUlt12FTuNz1LjzSxV7tsWt9T21T0Mr16G0_-P30y-H3FTkrbRXw-lDn5OPl-X3xytZvy9Xiac1yqXjPUpXnGiACzYVVNlZpnCMkIITgViAqmwmVRlBIhCxJdZryRGaFjiNlEWKQc3I35Xa-_RzG003tQo5VZRtsh2BEpLRSUTyCmhMxSXPfhuCxNJ13tfU7w8HswZoJrBnBml-wRo-m20P-kNVYHC1_JEeBnARhXDUb9GbbDr4Zf_4v9gcW7ILu</recordid><startdate>20210401</startdate><enddate>20210401</enddate><creator>Cabrales-Escobar, Iván Eduardo</creator><creator>Murcio-Pérez, Enrique</creator><creator>Albarrán-Sánchez, Alejandra</creator><general>Springer Singapore</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-2693-4031</orcidid></search><sort><creationdate>20210401</creationdate><title>IgG4-related disease manifesting as symptoms of appendicitis: Case report and literature review</title><author>Cabrales-Escobar, Iván Eduardo ; Murcio-Pérez, Enrique ; Albarrán-Sánchez, Alejandra</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c371t-97cc80040812a7a5795ce0602221a2ee7ab27940d3e0b69899163bd8547ae0503</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Abdominal Surgery</topic><topic>Case Report</topic><topic>Colorectal Surgery</topic><topic>Gastroenterology</topic><topic>Hepatology</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Surgical Oncology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cabrales-Escobar, Iván Eduardo</creatorcontrib><creatorcontrib>Murcio-Pérez, Enrique</creatorcontrib><creatorcontrib>Albarrán-Sánchez, Alejandra</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical journal of gastroenterology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cabrales-Escobar, Iván Eduardo</au><au>Murcio-Pérez, Enrique</au><au>Albarrán-Sánchez, Alejandra</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>IgG4-related disease manifesting as symptoms of appendicitis: Case report and literature review</atitle><jtitle>Clinical journal of gastroenterology</jtitle><stitle>Clin J Gastroenterol</stitle><addtitle>Clin J Gastroenterol</addtitle><date>2021-04-01</date><risdate>2021</risdate><volume>14</volume><issue>2</issue><spage>626</spage><epage>632</epage><pages>626-632</pages><issn>1865-7257</issn><eissn>1865-7265</eissn><abstract>Immunoglobulin G subclass 4 (IgG4)-related disease is a recently described fibroinflammatory condition. Reports of appendix involvement are extremely limited. A young man with abdominal pain and symptoms of acute appendicitis accompanied by the finding of an appendix-dependent tumor during surgery is presented. Histopathological study revealed lymphoplasmocytic infiltrate, storiform fibrosis and obliterative phlebitis. The number of IgG4-positive plasma cells was greater than 50 per high power field. Postsurgical steroid treatment and radiological findings are also described.</abstract><cop>Singapore</cop><pub>Springer Singapore</pub><pmid>33460019</pmid><doi>10.1007/s12328-020-01337-8</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0003-2693-4031</orcidid></addata></record> |
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subjects | Abdominal Surgery Case Report Colorectal Surgery Gastroenterology Hepatology Medicine Medicine & Public Health Surgical Oncology |
title | IgG4-related disease manifesting as symptoms of appendicitis: Case report and literature review |
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