T Cell Development: Old Tales Retold By Single-Cell RNA Sequencing

Mammalian T cell development initiates from the migration of hematopoietic progenitors to the thymus, which undergo cell proliferation, T-lineage specification and commitment, as well as positive and negative selection. These processes are precisely controlled at multiple levels and have been intens...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Trends in immunology 2021-02, Vol.42 (2), p.165-175
Hauptverfasser:	Liu, Chen, Lan, Yu, Liu, Bing, Zhang, Huiyuan, Hu, Hongbo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Animals Cell adhesion & migration Cell cycle Cell Differentiation Cell Lineage Cell Proliferation Gene expression Gene sequencing Hematopoietic Stem Cells Hemopoiesis Lymphocytes Lymphocytes T Molecular modelling Negative selection Principal components analysis Ribonucleic acid RNA Sequence Analysis, RNA T cell receptors T-Lymphocytes Thymus Thymus Gland
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!