Surface-Presentation of CpG and Protein–Antigen on Pathogen-Like Polymer Particles Generate Strong Prophylactic and Therapeutic Antitumor Protection

Despite significant efforts, development of clinically relevant prophylactic and therapeutic cancer vaccines has proven challenging. Cancer-associated antigens, which are often self-antigens, do not activate innate immune cells sufficiently, underscoring the need for codelivery of appropriate immune...

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Veröffentlicht in:ACS biomaterials science & engineering 2017-02, Vol.3 (2), p.169-178
Hauptverfasser: Dawson, Eileen, Leleux, Jardin A, Pradhan, Pallab, Roy, Krishnendu
Format: Artikel
Sprache:eng
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