Irreversible electroporation induces CD8+ T cell immune response against post-ablation hepatocellular carcinoma growth

Ablative treatment evokes antitumor immunity, but knowledge on the emerging irreversible electroporation (IRE)-induced immunity in hepatocellular carcinoma (HCC) is limited. To investigate the immune effects induced by IRE and its role in preventing post-ablation HCC progression, a C57BL/6J mouse mo...

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Veröffentlicht in:	Cancer letters 2021-04, Vol.503, p.1-10
Hauptverfasser:	Dai, Zihao, Wang, Zongren, Lei, Kai, Liao, Junbin, Peng, Zhenwei, Lin, Manxia, Liang, Ping, Yu, Jie, Peng, Sui, Chen, Shuling, Kuang, Ming
Format:	Artikel
Sprache:	eng
Schlagworte:	Ablation Antibodies Antitumor immunity Calreticulin CD4 antigen CD8 antigen Dendritic cells Electroporation Flow cytometry Hepatocellular carcinoma Hepatoma High temperature Immune response (cell-mediated) Immunosuppression Laboratory animals Liver cancer Local ablation Lymphocytes Lymphocytes T Lysates Metastases Metastasis PD-1 protein Spleen Tumor growth Tumorigenesis Tumors Vaccination γ-Interferon
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