Differentiation of glioblastoma stem cells promoted by miR-128 or miR-302a overexpression enhances senescence-associated cytotoxicity of axitinib

Abstract Despite the intense global efforts towards an effective treatment of glioblastoma (GB), current therapeutic options are unsatisfactory with a median survival time of 12–15 months after diagnosis, which has not improved significantly over more than a decade. The high tumoral heterogeneity co...

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Veröffentlicht in:	Human molecular genetics 2021-04, Vol.30 (3-4), p.160-171
Hauptverfasser:	Cardoso, Ana M, Morais, Catarina M, Pena, Frederico, Marante, Tânia, Cunha, Pedro P, Jurado, Amália S, Pedroso de Lima, Maria C
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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