Relationship between podoplanin-expressing cancer-associated fibroblasts and the immune microenvironment of early lung squamous cell carcinoma

•Podoplanin (PDPN)+ cancer associated fibroblasts (CAFs) promotes cancer progression in non-small cell lung cancer.•PDPN+ CAFs showed higher expression of transforming growth factor-β1 (TGFB1) gene.•PDPN+ CAFs were associated with CD204+ tumor-associated macrophage (TAM) infiltration.•PDPN + CAFs mi...

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Veröffentlicht in:	Lung cancer (Amsterdam, Netherlands) Netherlands), 2021-03, Vol.153, p.1-10
Hauptverfasser:	Suzuki, Jun, Aokage, Keiju, Neri, Shinya, Sakai, Takashi, Hashimoto, Hiroko, Su, Yinghan, Yamazaki, Shota, Nakamura, Hiroshi, Tane, Kenta, Miyoshi, Tomohiro, Sugano, Masato, Kojima, Motohiro, Fujii, Satoshi, Kuwata, Takeshi, Ochiai, Atsushi, Tsuboi, Masahiro, Ishii, Genichiro
Format:	Artikel
Sprache:	eng
Schlagworte:	cancer associated fibroblasts immune microenvironment lung squamous cell carcinoma podoplanin tumor-associated macrophage
Online-Zugang:	Volltext
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