Cysteamine assay for the evaluation of bioactive electrophiles

Covalent modifications of thiol and amine groups may control the function of proteins involved in the regulatory and signaling pathways of the cell. In this study, we developed a simple cysteamine assay which can be used to study the reactivity of electrophilic compounds towards primary amine and th...

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Veröffentlicht in:	Free radical biology & medicine 2021-02, Vol.164, p.381-389
Hauptverfasser:	Novák, David, Vrba, Jiří, Zatloukalová, Martina, Roubalová, Lenka, Stolarczyk, Krzysztof, Dorčák, Vlastimil, Vacek, Jan
Format:	Artikel
Sprache:	eng
Schlagworte:	Cysteamine assay Electrochemistry Hydrophilic interaction chromatography Nrf2 pathway Thiol reactivity
Online-Zugang:	Volltext
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