Design and synthesis of an anthranyl bridged optically active dinuclear iron(II)-ligand and evaluation of DNA-cleaving activity

[Display omitted] It is necessary to design a ligand that is compatible with the target molecule to optimally use the DNA-cleaving ability of metal complexes. In this study, we synthesized an optically active dinuclear ligand, (1R,1′R,2R,2′R)-N1,N1′-(anthracene-1,8-diylbis(methylene))bis(N2,N2-bis(p...

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Veröffentlicht in:	Bioorganic & medicinal chemistry letters 2021-03, Vol.35, p.127782-127782, Article 127782
Hauptverfasser:	Ichimaru, Yoshimi, Kato, Koichi, Okuno, Yoshinori, Yamaguchi, Yoshihiro, Jin, Wanchun, Fujita, Mikako, Otsuka, Masami, Imai, Masanori, Kurosaki, Hiromasa
Format:	Artikel
Sprache:	eng
Schlagworte:	Anthracene AT-rich Dinuclear ligand DNA-cleaving activity Iron complex
Online-Zugang:	Volltext
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