Histopathological features of HER2 overexpression in uterine carcinosarcoma: proposal for requirements in HER2 testing for targeted therapy

Uterine carcinosarcoma (UCS) is an uncommon and highly aggressive tumor. There is no HER2 testing protocol for UCS despite the development of HER2 antibody conjugates. We aimed to elucidate histopathological HER2 expression details in UCS, to compare HER2 scores between ASCO/CAP criteria for gastric...

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Veröffentlicht in:	Virchows Archiv : an international journal of pathology 2021-06, Vol.478 (6), p.1161-1171
Hauptverfasser:	Yoshida, Hiroshi, Nishikawa, Tadaaki, Matsumoto, Koji, Mori, Masahiko, Hirashima, Yasuyuki, Takehara, Kazuhiro, Ariyoshi, Kazuya, Hasegawa, Kosei, Yonemori, Kan
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Breast cancer Criteria ErbB-2 protein Gastric cancer Gene amplification Heterogeneity Immunohistochemistry Medicine Medicine & Public Health Metastases Original Article Pathology Staining Test procedures Uterus
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