Alpha-asarone Improves Cognitive Function of APP/PS1 Mice and Reducing Aβ42, P-tau and Neuroinflammation, and Promoting Neuron Survival in the Hippocampus

[Display omitted] •Alpha-asarone improves the cognitive function of APP/PS1 transgenic mice.•Alpha-asarone reduced Aβ42 and p-tau protein levels in the hippocampus.•Alpha-asarone reduced the brain GFAP expression and alleviated neuroinflammation.•Alpha-asarone decreased autophagosomes and promoted h...

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Veröffentlicht in:	Neuroscience 2021-03, Vol.458, p.141-152
Hauptverfasser:	Zeng, Lili, Zhang, Di, Liu, Qi, Zhang, Jian, Mu, Keman, Gao, Xiaofeng, Zhang, Kun, Li, Hui, Wang, Qiantao, Zheng, Yongxiang, Mao, Shengjun
Format:	Artikel
Sprache:	eng
Schlagworte:	alpha-asarone Alzheimer’s disease APP/PS1 transgenic mice autophagy neuroinflammation
Online-Zugang:	Volltext
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