Socioeconomic disparities in prehospital factors and survival after out-of-hospital cardiac arrest

ObjectiveIt remains unknown whether patient socioeconomic factors affect interventions and survival after out-of-hospital cardiac arrest (OHCA), and whether a socioeconomic effect on bystander interventions affects survival. Therefore, this study examined patient socioeconomic disparities in prehosp...

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Veröffentlicht in:Heart (British Cardiac Society) 2021-04, Vol.107 (8), p.627-634
Hauptverfasser: Møller, Sidsel, Wissenberg, Mads, Starkopf, Liis, Kragholm, Kristian, Hansen, Steen M, Ringgren, Kristian Bundgaard, Folke, Fredrik, Andersen, Julie, Malta Hansen, Carolina, Lippert, Freddy, Koeber, Lars, Gislason, Gunnar Hilmar, Torp-Pedersen, Christian, Gerds, Thomas A
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container_end_page 634
container_issue 8
container_start_page 627
container_title Heart (British Cardiac Society)
container_volume 107
creator Møller, Sidsel
Wissenberg, Mads
Starkopf, Liis
Kragholm, Kristian
Hansen, Steen M
Ringgren, Kristian Bundgaard
Folke, Fredrik
Andersen, Julie
Malta Hansen, Carolina
Lippert, Freddy
Koeber, Lars
Gislason, Gunnar Hilmar
Torp-Pedersen, Christian
Gerds, Thomas A
description ObjectiveIt remains unknown whether patient socioeconomic factors affect interventions and survival after out-of-hospital cardiac arrest (OHCA), and whether a socioeconomic effect on bystander interventions affects survival. Therefore, this study examined patient socioeconomic disparities in prehospital factors and survival.MethodsFrom the Danish Cardiac Arrest Registry, patients with OHCA ≥30 years were identified, 2001–2014, and divided into quartiles of household income (highest, high, low, lowest). Associations between income and bystander cardiopulmonary resuscitation (CPR) and 30-day survival with bystander CPR as mediator were analysed by logistic regression and mediation analysis in private witnessed, public witnessed, private unwitnessed and public unwitnessed arrests, adjusted for confounders.ResultsWe included 21 480 patients. Highest income patients were younger, had higher education and were less comorbid relative to lowest income patients. They had higher odds for bystander CPR with the biggest difference in private unwitnessed arrests (OR 1.74, 95% CI 1.47 to 2.05). For 30-day survival, the biggest differences were in public witnessed arrests with 26.0% (95% CI 22.4% to 29.7%) higher survival in highest income compared with lowest income patients. Had bystander CPR been the same for lowest income as for highest income patients, then survival would be 25.3% (95% CI 21.5% to 29.0%) higher in highest income compared with lowest income patients, resulting in elimination of 0.79% (95% CI 0.08% to 1.50%) of the income disparity in survival. Similar trends but smaller were observed in low and high-income patients, the other three subgroups and with education instead of income. From 2002 to 2014, increases were observed in both CPR and survival in all income groups.ConclusionOverall, lower socioeconomic status was associated with poorer prehospital factors and survival after OHCA that was not explained by patient or cardiac arrest-related factors.
doi_str_mv 10.1136/heartjnl-2020-317761
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Therefore, this study examined patient socioeconomic disparities in prehospital factors and survival.MethodsFrom the Danish Cardiac Arrest Registry, patients with OHCA ≥30 years were identified, 2001–2014, and divided into quartiles of household income (highest, high, low, lowest). Associations between income and bystander cardiopulmonary resuscitation (CPR) and 30-day survival with bystander CPR as mediator were analysed by logistic regression and mediation analysis in private witnessed, public witnessed, private unwitnessed and public unwitnessed arrests, adjusted for confounders.ResultsWe included 21 480 patients. Highest income patients were younger, had higher education and were less comorbid relative to lowest income patients. They had higher odds for bystander CPR with the biggest difference in private unwitnessed arrests (OR 1.74, 95% CI 1.47 to 2.05). For 30-day survival, the biggest differences were in public witnessed arrests with 26.0% (95% CI 22.4% to 29.7%) higher survival in highest income compared with lowest income patients. Had bystander CPR been the same for lowest income as for highest income patients, then survival would be 25.3% (95% CI 21.5% to 29.0%) higher in highest income compared with lowest income patients, resulting in elimination of 0.79% (95% CI 0.08% to 1.50%) of the income disparity in survival. Similar trends but smaller were observed in low and high-income patients, the other three subgroups and with education instead of income. From 2002 to 2014, increases were observed in both CPR and survival in all income groups.ConclusionOverall, lower socioeconomic status was associated with poorer prehospital factors and survival after OHCA that was not explained by patient or cardiac arrest-related factors.</description><identifier>ISSN: 1355-6037</identifier><identifier>EISSN: 1468-201X</identifier><identifier>DOI: 10.1136/heartjnl-2020-317761</identifier><identifier>PMID: 33419881</identifier><language>eng</language><publisher>England: BMJ Publishing Group LTD</publisher><subject>Age ; Cardiac arrest ; Cardiopulmonary resuscitation ; Chronic obstructive pulmonary disease ; CPR ; Disease ; Education ; Family income ; Heart ; Hospitals ; Households ; Medical prognosis ; Patients ; Secondary education ; Socioeconomic factors ; Trends</subject><ispartof>Heart (British Cardiac Society), 2021-04, Vol.107 (8), p.627-634</ispartof><rights>Author(s) (or their employer(s)) 2021. No commercial re-use. See rights and permissions. Published by BMJ.</rights><rights>2021 Author(s) (or their employer(s)) 2021. No commercial re-use. See rights and permissions. Published by BMJ.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b375t-ffc078bf3c1b97540ee8605f3c710f297b0b4cbeaad1586e0f0f38c3d3325e933</citedby><cites>FETCH-LOGICAL-b375t-ffc078bf3c1b97540ee8605f3c710f297b0b4cbeaad1586e0f0f38c3d3325e933</cites><orcidid>0000-0002-5004-6694 ; 0000-0002-8079-6189</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785,27926,27927</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33419881$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Møller, Sidsel</creatorcontrib><creatorcontrib>Wissenberg, Mads</creatorcontrib><creatorcontrib>Starkopf, Liis</creatorcontrib><creatorcontrib>Kragholm, Kristian</creatorcontrib><creatorcontrib>Hansen, Steen M</creatorcontrib><creatorcontrib>Ringgren, Kristian Bundgaard</creatorcontrib><creatorcontrib>Folke, Fredrik</creatorcontrib><creatorcontrib>Andersen, Julie</creatorcontrib><creatorcontrib>Malta Hansen, Carolina</creatorcontrib><creatorcontrib>Lippert, Freddy</creatorcontrib><creatorcontrib>Koeber, Lars</creatorcontrib><creatorcontrib>Gislason, Gunnar Hilmar</creatorcontrib><creatorcontrib>Torp-Pedersen, Christian</creatorcontrib><creatorcontrib>Gerds, Thomas A</creatorcontrib><title>Socioeconomic disparities in prehospital factors and survival after out-of-hospital cardiac arrest</title><title>Heart (British Cardiac Society)</title><addtitle>Heart</addtitle><description>ObjectiveIt remains unknown whether patient socioeconomic factors affect interventions and survival after out-of-hospital cardiac arrest (OHCA), and whether a socioeconomic effect on bystander interventions affects survival. Therefore, this study examined patient socioeconomic disparities in prehospital factors and survival.MethodsFrom the Danish Cardiac Arrest Registry, patients with OHCA ≥30 years were identified, 2001–2014, and divided into quartiles of household income (highest, high, low, lowest). Associations between income and bystander cardiopulmonary resuscitation (CPR) and 30-day survival with bystander CPR as mediator were analysed by logistic regression and mediation analysis in private witnessed, public witnessed, private unwitnessed and public unwitnessed arrests, adjusted for confounders.ResultsWe included 21 480 patients. Highest income patients were younger, had higher education and were less comorbid relative to lowest income patients. They had higher odds for bystander CPR with the biggest difference in private unwitnessed arrests (OR 1.74, 95% CI 1.47 to 2.05). For 30-day survival, the biggest differences were in public witnessed arrests with 26.0% (95% CI 22.4% to 29.7%) higher survival in highest income compared with lowest income patients. Had bystander CPR been the same for lowest income as for highest income patients, then survival would be 25.3% (95% CI 21.5% to 29.0%) higher in highest income compared with lowest income patients, resulting in elimination of 0.79% (95% CI 0.08% to 1.50%) of the income disparity in survival. Similar trends but smaller were observed in low and high-income patients, the other three subgroups and with education instead of income. 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Medical Complete (Alumni)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Heart (British Cardiac Society)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Møller, Sidsel</au><au>Wissenberg, Mads</au><au>Starkopf, Liis</au><au>Kragholm, Kristian</au><au>Hansen, Steen M</au><au>Ringgren, Kristian Bundgaard</au><au>Folke, Fredrik</au><au>Andersen, Julie</au><au>Malta Hansen, Carolina</au><au>Lippert, Freddy</au><au>Koeber, Lars</au><au>Gislason, Gunnar Hilmar</au><au>Torp-Pedersen, Christian</au><au>Gerds, Thomas A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Socioeconomic disparities in prehospital factors and survival after out-of-hospital cardiac arrest</atitle><jtitle>Heart (British Cardiac Society)</jtitle><addtitle>Heart</addtitle><date>2021-04</date><risdate>2021</risdate><volume>107</volume><issue>8</issue><spage>627</spage><epage>634</epage><pages>627-634</pages><issn>1355-6037</issn><eissn>1468-201X</eissn><abstract>ObjectiveIt remains unknown whether patient socioeconomic factors affect interventions and survival after out-of-hospital cardiac arrest (OHCA), and whether a socioeconomic effect on bystander interventions affects survival. Therefore, this study examined patient socioeconomic disparities in prehospital factors and survival.MethodsFrom the Danish Cardiac Arrest Registry, patients with OHCA ≥30 years were identified, 2001–2014, and divided into quartiles of household income (highest, high, low, lowest). Associations between income and bystander cardiopulmonary resuscitation (CPR) and 30-day survival with bystander CPR as mediator were analysed by logistic regression and mediation analysis in private witnessed, public witnessed, private unwitnessed and public unwitnessed arrests, adjusted for confounders.ResultsWe included 21 480 patients. Highest income patients were younger, had higher education and were less comorbid relative to lowest income patients. They had higher odds for bystander CPR with the biggest difference in private unwitnessed arrests (OR 1.74, 95% CI 1.47 to 2.05). For 30-day survival, the biggest differences were in public witnessed arrests with 26.0% (95% CI 22.4% to 29.7%) higher survival in highest income compared with lowest income patients. Had bystander CPR been the same for lowest income as for highest income patients, then survival would be 25.3% (95% CI 21.5% to 29.0%) higher in highest income compared with lowest income patients, resulting in elimination of 0.79% (95% CI 0.08% to 1.50%) of the income disparity in survival. Similar trends but smaller were observed in low and high-income patients, the other three subgroups and with education instead of income. From 2002 to 2014, increases were observed in both CPR and survival in all income groups.ConclusionOverall, lower socioeconomic status was associated with poorer prehospital factors and survival after OHCA that was not explained by patient or cardiac arrest-related factors.</abstract><cop>England</cop><pub>BMJ Publishing Group LTD</pub><pmid>33419881</pmid><doi>10.1136/heartjnl-2020-317761</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0002-5004-6694</orcidid><orcidid>https://orcid.org/0000-0002-8079-6189</orcidid></addata></record>
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subjects Age
Cardiac arrest
Cardiopulmonary resuscitation
Chronic obstructive pulmonary disease
CPR
Disease
Education
Family income
Heart
Hospitals
Households
Medical prognosis
Patients
Secondary education
Socioeconomic factors
Trends
title Socioeconomic disparities in prehospital factors and survival after out-of-hospital cardiac arrest
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