Stroke Acute Management and Outcomes During the COVID-19 Outbreak: A Cohort Study From the Madrid Stroke Network
The coronavirus disease 2019 (COVID-19) outbreak has added challenges to providing quality acute stroke care due to the reallocation of stroke resources to COVID-19. Case series suggest that patients with COVID-19 have more severe strokes; however, no large series have compared stroke outcomes with...
Gespeichert in:
| Veröffentlicht in: | Stroke (1970) 2021-02, Vol.52 (2), p.552-562 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 562 |
|---|---|
| container_issue | 2 |
| container_start_page | 552 |
| container_title | Stroke (1970) |
| container_volume | 52 |
| creator | Fuentes, Blanca Alonso de Leciñana, María García-Madrona, Sebastián Díaz-Otero, Fernando Aguirre, Clara Calleja, Patricia Egido, José A. Carneado-Ruiz, Joaquín Ruiz-Ares, Gerardo Rodríguez-Pardo, Jorge Rodríguez-López, Ángela Ximénez-Carrillo, Álvaro de Felipe, Alicia Ostos, Fernando González-Ortega, Guillermo Simal, Patricia Gómez Escalonilla, Carlos I. Gómez-Porro-Sánchez, Pablo Desanvicente, Zayrho Reig, Gemma Gil-Núñez, Antonio Masjuán, Jaime Díez-Tejedor, Exuperio |
| description | The coronavirus disease 2019 (COVID-19) outbreak has added challenges to providing quality acute stroke care due to the reallocation of stroke resources to COVID-19. Case series suggest that patients with COVID-19 have more severe strokes; however, no large series have compared stroke outcomes with contemporary non-COVID-19 patients. Purpose was to analyze the impact of COVID-19 pandemic in stroke care and to evaluate stroke outcomes according to the diagnosis of COVID-19.
Retrospective multicenter cohort study including consecutive acute stroke patients admitted to 7 stroke centers from February 25 to April 25, 2020 (first 2 months of the COVID-19 outbreak in Madrid). The quality of stroke care was measured by the number of admissions, recanalization treatments, and time metrics. The primary outcome was death or dependence at discharge.
A total of 550 acute stroke patients were admitted. A significant reduction in the number of admissions and secondary interhospital transfers was found. COVID-19 was confirmed in 105 (19.1%) patients, and a further 19 patients were managed as suspected COVID-19 (3.5%). No differences were found in the rates of reperfusion therapies in ischemic strokes (45.5% non-COVID-19, 35.7% confirmed COVID-19, and 40% suspected COVID-19;
=0.265). However, the COVID-19 group had longer median door-to-puncture time (110 versus 80 minutes), which was associated with the performance of chest computed tomography. Multivariate analysis confirmed poorer outcomes for confirmed or suspected COVID-19 (adjusted odds ratios, 2.05 [95% CI, 1.12-3.76] and 3.56 [95% CI, 1.15-11.05], respectively).
This study confirms that patients with COVID-19 have more severe strokes and poorer outcomes despite similar acute management. A well-established stroke care network helps to diminish the impact of such an outbreak in stroke care, reducing secondary transfers and allowing maintenance of reperfusion therapies, with a minor impact on door-to-puncture times, which were longer in patients who underwent chest computed tomography. |
| doi_str_mv | 10.1161/STROKEAHA.120.031769 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2476129326</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2476129326</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3012-62e94ab65169d581c54199587db128d77fa1f860b21f4595f0af1bd36e2d335d3</originalsourceid><addsrcrecordid>eNpFkVFv0zAUhS0EYmXwDxDyIy_pfG3HiXmLuo1NbFSig1fLiW_W0iQutqNq_550LePp6uqec670HUI-ApsDKLhYPfxYfruqbqo5cDZnAgqlX5EZ5FxmUvHyNZkxJnTGpdZn5F2MvxljXJT5W3ImhGSqLPiM7FYp-C3SqhkT0ns72EfscUjUDo4ux9T4HiO9HMNmeKRpjXSx_HV7mYE-HOuAdvuFVnTh1z4kukqje6LXwffP0nvrwsbR04fvmPY-bN-TN63tIn44zXPy8_rqYXGT3S2_3i6qu6wRDHimOGppa5WD0i4vocklaJ2XhauBl64oWgttqVjNoZW5zltmW6idUMidELkT5-TzMXcX_J8RYzL9JjbYdXZAP0bDZaGAa8HVJJVHaRN8jAFbswub3oYnA8wcWJsX1mZibY6sJ9un04ex7tG9mP7B_Z-7913CELfduMdg1mi7tDZTG6xQBcs448D4tGWHgrj4C1v6iLU</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2476129326</pqid></control><display><type>article</type><title>Stroke Acute Management and Outcomes During the COVID-19 Outbreak: A Cohort Study From the Madrid Stroke Network</title><source>MEDLINE</source><source>American Heart Association Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Alma/SFX Local Collection</source><source>Journals@Ovid Complete</source><creator>Fuentes, Blanca ; Alonso de Leciñana, María ; García-Madrona, Sebastián ; Díaz-Otero, Fernando ; Aguirre, Clara ; Calleja, Patricia ; Egido, José A. ; Carneado-Ruiz, Joaquín ; Ruiz-Ares, Gerardo ; Rodríguez-Pardo, Jorge ; Rodríguez-López, Ángela ; Ximénez-Carrillo, Álvaro ; de Felipe, Alicia ; Ostos, Fernando ; González-Ortega, Guillermo ; Simal, Patricia ; Gómez Escalonilla, Carlos I. ; Gómez-Porro-Sánchez, Pablo ; Desanvicente, Zayrho ; Reig, Gemma ; Gil-Núñez, Antonio ; Masjuán, Jaime ; Díez-Tejedor, Exuperio</creator><creatorcontrib>Fuentes, Blanca ; Alonso de Leciñana, María ; García-Madrona, Sebastián ; Díaz-Otero, Fernando ; Aguirre, Clara ; Calleja, Patricia ; Egido, José A. ; Carneado-Ruiz, Joaquín ; Ruiz-Ares, Gerardo ; Rodríguez-Pardo, Jorge ; Rodríguez-López, Ángela ; Ximénez-Carrillo, Álvaro ; de Felipe, Alicia ; Ostos, Fernando ; González-Ortega, Guillermo ; Simal, Patricia ; Gómez Escalonilla, Carlos I. ; Gómez-Porro-Sánchez, Pablo ; Desanvicente, Zayrho ; Reig, Gemma ; Gil-Núñez, Antonio ; Masjuán, Jaime ; Díez-Tejedor, Exuperio</creatorcontrib><description>The coronavirus disease 2019 (COVID-19) outbreak has added challenges to providing quality acute stroke care due to the reallocation of stroke resources to COVID-19. Case series suggest that patients with COVID-19 have more severe strokes; however, no large series have compared stroke outcomes with contemporary non-COVID-19 patients. Purpose was to analyze the impact of COVID-19 pandemic in stroke care and to evaluate stroke outcomes according to the diagnosis of COVID-19.
Retrospective multicenter cohort study including consecutive acute stroke patients admitted to 7 stroke centers from February 25 to April 25, 2020 (first 2 months of the COVID-19 outbreak in Madrid). The quality of stroke care was measured by the number of admissions, recanalization treatments, and time metrics. The primary outcome was death or dependence at discharge.
A total of 550 acute stroke patients were admitted. A significant reduction in the number of admissions and secondary interhospital transfers was found. COVID-19 was confirmed in 105 (19.1%) patients, and a further 19 patients were managed as suspected COVID-19 (3.5%). No differences were found in the rates of reperfusion therapies in ischemic strokes (45.5% non-COVID-19, 35.7% confirmed COVID-19, and 40% suspected COVID-19;
=0.265). However, the COVID-19 group had longer median door-to-puncture time (110 versus 80 minutes), which was associated with the performance of chest computed tomography. Multivariate analysis confirmed poorer outcomes for confirmed or suspected COVID-19 (adjusted odds ratios, 2.05 [95% CI, 1.12-3.76] and 3.56 [95% CI, 1.15-11.05], respectively).
This study confirms that patients with COVID-19 have more severe strokes and poorer outcomes despite similar acute management. A well-established stroke care network helps to diminish the impact of such an outbreak in stroke care, reducing secondary transfers and allowing maintenance of reperfusion therapies, with a minor impact on door-to-puncture times, which were longer in patients who underwent chest computed tomography.</description><identifier>ISSN: 0039-2499</identifier><identifier>EISSN: 1524-4628</identifier><identifier>DOI: 10.1161/STROKEAHA.120.031769</identifier><identifier>PMID: 33406872</identifier><language>eng</language><publisher>United States: American Heart Association, Inc</publisher><subject>Aged ; Aged, 80 and over ; COVID-19 - complications ; COVID-19 - epidemiology ; Disease Outbreaks - prevention & control ; Female ; Hospitalization - statistics & numerical data ; Humans ; Male ; Middle Aged ; Retrospective Studies ; SARS-CoV-2 - pathogenicity ; Stroke - epidemiology ; Stroke - virology</subject><ispartof>Stroke (1970), 2021-02, Vol.52 (2), p.552-562</ispartof><rights>American Heart Association, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c3012-62e94ab65169d581c54199587db128d77fa1f860b21f4595f0af1bd36e2d335d3</cites><orcidid>0000-0002-4302-6580 ; 0000-0002-0363-862X ; 0000-0003-1964-7739 ; 0000-0002-8487-6514</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,3674,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33406872$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Fuentes, Blanca</creatorcontrib><creatorcontrib>Alonso de Leciñana, María</creatorcontrib><creatorcontrib>García-Madrona, Sebastián</creatorcontrib><creatorcontrib>Díaz-Otero, Fernando</creatorcontrib><creatorcontrib>Aguirre, Clara</creatorcontrib><creatorcontrib>Calleja, Patricia</creatorcontrib><creatorcontrib>Egido, José A.</creatorcontrib><creatorcontrib>Carneado-Ruiz, Joaquín</creatorcontrib><creatorcontrib>Ruiz-Ares, Gerardo</creatorcontrib><creatorcontrib>Rodríguez-Pardo, Jorge</creatorcontrib><creatorcontrib>Rodríguez-López, Ángela</creatorcontrib><creatorcontrib>Ximénez-Carrillo, Álvaro</creatorcontrib><creatorcontrib>de Felipe, Alicia</creatorcontrib><creatorcontrib>Ostos, Fernando</creatorcontrib><creatorcontrib>González-Ortega, Guillermo</creatorcontrib><creatorcontrib>Simal, Patricia</creatorcontrib><creatorcontrib>Gómez Escalonilla, Carlos I.</creatorcontrib><creatorcontrib>Gómez-Porro-Sánchez, Pablo</creatorcontrib><creatorcontrib>Desanvicente, Zayrho</creatorcontrib><creatorcontrib>Reig, Gemma</creatorcontrib><creatorcontrib>Gil-Núñez, Antonio</creatorcontrib><creatorcontrib>Masjuán, Jaime</creatorcontrib><creatorcontrib>Díez-Tejedor, Exuperio</creatorcontrib><title>Stroke Acute Management and Outcomes During the COVID-19 Outbreak: A Cohort Study From the Madrid Stroke Network</title><title>Stroke (1970)</title><addtitle>Stroke</addtitle><description>The coronavirus disease 2019 (COVID-19) outbreak has added challenges to providing quality acute stroke care due to the reallocation of stroke resources to COVID-19. Case series suggest that patients with COVID-19 have more severe strokes; however, no large series have compared stroke outcomes with contemporary non-COVID-19 patients. Purpose was to analyze the impact of COVID-19 pandemic in stroke care and to evaluate stroke outcomes according to the diagnosis of COVID-19.
Retrospective multicenter cohort study including consecutive acute stroke patients admitted to 7 stroke centers from February 25 to April 25, 2020 (first 2 months of the COVID-19 outbreak in Madrid). The quality of stroke care was measured by the number of admissions, recanalization treatments, and time metrics. The primary outcome was death or dependence at discharge.
A total of 550 acute stroke patients were admitted. A significant reduction in the number of admissions and secondary interhospital transfers was found. COVID-19 was confirmed in 105 (19.1%) patients, and a further 19 patients were managed as suspected COVID-19 (3.5%). No differences were found in the rates of reperfusion therapies in ischemic strokes (45.5% non-COVID-19, 35.7% confirmed COVID-19, and 40% suspected COVID-19;
=0.265). However, the COVID-19 group had longer median door-to-puncture time (110 versus 80 minutes), which was associated with the performance of chest computed tomography. Multivariate analysis confirmed poorer outcomes for confirmed or suspected COVID-19 (adjusted odds ratios, 2.05 [95% CI, 1.12-3.76] and 3.56 [95% CI, 1.15-11.05], respectively).
This study confirms that patients with COVID-19 have more severe strokes and poorer outcomes despite similar acute management. A well-established stroke care network helps to diminish the impact of such an outbreak in stroke care, reducing secondary transfers and allowing maintenance of reperfusion therapies, with a minor impact on door-to-puncture times, which were longer in patients who underwent chest computed tomography.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>COVID-19 - complications</subject><subject>COVID-19 - epidemiology</subject><subject>Disease Outbreaks - prevention & control</subject><subject>Female</subject><subject>Hospitalization - statistics & numerical data</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Retrospective Studies</subject><subject>SARS-CoV-2 - pathogenicity</subject><subject>Stroke - epidemiology</subject><subject>Stroke - virology</subject><issn>0039-2499</issn><issn>1524-4628</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkVFv0zAUhS0EYmXwDxDyIy_pfG3HiXmLuo1NbFSig1fLiW_W0iQutqNq_550LePp6uqec670HUI-ApsDKLhYPfxYfruqbqo5cDZnAgqlX5EZ5FxmUvHyNZkxJnTGpdZn5F2MvxljXJT5W3ImhGSqLPiM7FYp-C3SqhkT0ns72EfscUjUDo4ux9T4HiO9HMNmeKRpjXSx_HV7mYE-HOuAdvuFVnTh1z4kukqje6LXwffP0nvrwsbR04fvmPY-bN-TN63tIn44zXPy8_rqYXGT3S2_3i6qu6wRDHimOGppa5WD0i4vocklaJ2XhauBl64oWgttqVjNoZW5zltmW6idUMidELkT5-TzMXcX_J8RYzL9JjbYdXZAP0bDZaGAa8HVJJVHaRN8jAFbswub3oYnA8wcWJsX1mZibY6sJ9un04ex7tG9mP7B_Z-7913CELfduMdg1mi7tDZTG6xQBcs448D4tGWHgrj4C1v6iLU</recordid><startdate>20210201</startdate><enddate>20210201</enddate><creator>Fuentes, Blanca</creator><creator>Alonso de Leciñana, María</creator><creator>García-Madrona, Sebastián</creator><creator>Díaz-Otero, Fernando</creator><creator>Aguirre, Clara</creator><creator>Calleja, Patricia</creator><creator>Egido, José A.</creator><creator>Carneado-Ruiz, Joaquín</creator><creator>Ruiz-Ares, Gerardo</creator><creator>Rodríguez-Pardo, Jorge</creator><creator>Rodríguez-López, Ángela</creator><creator>Ximénez-Carrillo, Álvaro</creator><creator>de Felipe, Alicia</creator><creator>Ostos, Fernando</creator><creator>González-Ortega, Guillermo</creator><creator>Simal, Patricia</creator><creator>Gómez Escalonilla, Carlos I.</creator><creator>Gómez-Porro-Sánchez, Pablo</creator><creator>Desanvicente, Zayrho</creator><creator>Reig, Gemma</creator><creator>Gil-Núñez, Antonio</creator><creator>Masjuán, Jaime</creator><creator>Díez-Tejedor, Exuperio</creator><general>American Heart Association, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-4302-6580</orcidid><orcidid>https://orcid.org/0000-0002-0363-862X</orcidid><orcidid>https://orcid.org/0000-0003-1964-7739</orcidid><orcidid>https://orcid.org/0000-0002-8487-6514</orcidid></search><sort><creationdate>20210201</creationdate><title>Stroke Acute Management and Outcomes During the COVID-19 Outbreak: A Cohort Study From the Madrid Stroke Network</title><author>Fuentes, Blanca ; Alonso de Leciñana, María ; García-Madrona, Sebastián ; Díaz-Otero, Fernando ; Aguirre, Clara ; Calleja, Patricia ; Egido, José A. ; Carneado-Ruiz, Joaquín ; Ruiz-Ares, Gerardo ; Rodríguez-Pardo, Jorge ; Rodríguez-López, Ángela ; Ximénez-Carrillo, Álvaro ; de Felipe, Alicia ; Ostos, Fernando ; González-Ortega, Guillermo ; Simal, Patricia ; Gómez Escalonilla, Carlos I. ; Gómez-Porro-Sánchez, Pablo ; Desanvicente, Zayrho ; Reig, Gemma ; Gil-Núñez, Antonio ; Masjuán, Jaime ; Díez-Tejedor, Exuperio</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3012-62e94ab65169d581c54199587db128d77fa1f860b21f4595f0af1bd36e2d335d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>COVID-19 - complications</topic><topic>COVID-19 - epidemiology</topic><topic>Disease Outbreaks - prevention & control</topic><topic>Female</topic><topic>Hospitalization - statistics & numerical data</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Retrospective Studies</topic><topic>SARS-CoV-2 - pathogenicity</topic><topic>Stroke - epidemiology</topic><topic>Stroke - virology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fuentes, Blanca</creatorcontrib><creatorcontrib>Alonso de Leciñana, María</creatorcontrib><creatorcontrib>García-Madrona, Sebastián</creatorcontrib><creatorcontrib>Díaz-Otero, Fernando</creatorcontrib><creatorcontrib>Aguirre, Clara</creatorcontrib><creatorcontrib>Calleja, Patricia</creatorcontrib><creatorcontrib>Egido, José A.</creatorcontrib><creatorcontrib>Carneado-Ruiz, Joaquín</creatorcontrib><creatorcontrib>Ruiz-Ares, Gerardo</creatorcontrib><creatorcontrib>Rodríguez-Pardo, Jorge</creatorcontrib><creatorcontrib>Rodríguez-López, Ángela</creatorcontrib><creatorcontrib>Ximénez-Carrillo, Álvaro</creatorcontrib><creatorcontrib>de Felipe, Alicia</creatorcontrib><creatorcontrib>Ostos, Fernando</creatorcontrib><creatorcontrib>González-Ortega, Guillermo</creatorcontrib><creatorcontrib>Simal, Patricia</creatorcontrib><creatorcontrib>Gómez Escalonilla, Carlos I.</creatorcontrib><creatorcontrib>Gómez-Porro-Sánchez, Pablo</creatorcontrib><creatorcontrib>Desanvicente, Zayrho</creatorcontrib><creatorcontrib>Reig, Gemma</creatorcontrib><creatorcontrib>Gil-Núñez, Antonio</creatorcontrib><creatorcontrib>Masjuán, Jaime</creatorcontrib><creatorcontrib>Díez-Tejedor, Exuperio</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Stroke (1970)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fuentes, Blanca</au><au>Alonso de Leciñana, María</au><au>García-Madrona, Sebastián</au><au>Díaz-Otero, Fernando</au><au>Aguirre, Clara</au><au>Calleja, Patricia</au><au>Egido, José A.</au><au>Carneado-Ruiz, Joaquín</au><au>Ruiz-Ares, Gerardo</au><au>Rodríguez-Pardo, Jorge</au><au>Rodríguez-López, Ángela</au><au>Ximénez-Carrillo, Álvaro</au><au>de Felipe, Alicia</au><au>Ostos, Fernando</au><au>González-Ortega, Guillermo</au><au>Simal, Patricia</au><au>Gómez Escalonilla, Carlos I.</au><au>Gómez-Porro-Sánchez, Pablo</au><au>Desanvicente, Zayrho</au><au>Reig, Gemma</au><au>Gil-Núñez, Antonio</au><au>Masjuán, Jaime</au><au>Díez-Tejedor, Exuperio</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Stroke Acute Management and Outcomes During the COVID-19 Outbreak: A Cohort Study From the Madrid Stroke Network</atitle><jtitle>Stroke (1970)</jtitle><addtitle>Stroke</addtitle><date>2021-02-01</date><risdate>2021</risdate><volume>52</volume><issue>2</issue><spage>552</spage><epage>562</epage><pages>552-562</pages><issn>0039-2499</issn><eissn>1524-4628</eissn><abstract>The coronavirus disease 2019 (COVID-19) outbreak has added challenges to providing quality acute stroke care due to the reallocation of stroke resources to COVID-19. Case series suggest that patients with COVID-19 have more severe strokes; however, no large series have compared stroke outcomes with contemporary non-COVID-19 patients. Purpose was to analyze the impact of COVID-19 pandemic in stroke care and to evaluate stroke outcomes according to the diagnosis of COVID-19.
Retrospective multicenter cohort study including consecutive acute stroke patients admitted to 7 stroke centers from February 25 to April 25, 2020 (first 2 months of the COVID-19 outbreak in Madrid). The quality of stroke care was measured by the number of admissions, recanalization treatments, and time metrics. The primary outcome was death or dependence at discharge.
A total of 550 acute stroke patients were admitted. A significant reduction in the number of admissions and secondary interhospital transfers was found. COVID-19 was confirmed in 105 (19.1%) patients, and a further 19 patients were managed as suspected COVID-19 (3.5%). No differences were found in the rates of reperfusion therapies in ischemic strokes (45.5% non-COVID-19, 35.7% confirmed COVID-19, and 40% suspected COVID-19;
=0.265). However, the COVID-19 group had longer median door-to-puncture time (110 versus 80 minutes), which was associated with the performance of chest computed tomography. Multivariate analysis confirmed poorer outcomes for confirmed or suspected COVID-19 (adjusted odds ratios, 2.05 [95% CI, 1.12-3.76] and 3.56 [95% CI, 1.15-11.05], respectively).
This study confirms that patients with COVID-19 have more severe strokes and poorer outcomes despite similar acute management. A well-established stroke care network helps to diminish the impact of such an outbreak in stroke care, reducing secondary transfers and allowing maintenance of reperfusion therapies, with a minor impact on door-to-puncture times, which were longer in patients who underwent chest computed tomography.</abstract><cop>United States</cop><pub>American Heart Association, Inc</pub><pmid>33406872</pmid><doi>10.1161/STROKEAHA.120.031769</doi><tpages>11</tpages><orcidid>https://orcid.org/0000-0002-4302-6580</orcidid><orcidid>https://orcid.org/0000-0002-0363-862X</orcidid><orcidid>https://orcid.org/0000-0003-1964-7739</orcidid><orcidid>https://orcid.org/0000-0002-8487-6514</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0039-2499 |
| ispartof | Stroke (1970), 2021-02, Vol.52 (2), p.552-562 |
| issn | 0039-2499 1524-4628 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2476129326 |
| source | MEDLINE; American Heart Association Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection; Journals@Ovid Complete |
| subjects | Aged Aged, 80 and over COVID-19 - complications COVID-19 - epidemiology Disease Outbreaks - prevention & control Female Hospitalization - statistics & numerical data Humans Male Middle Aged Retrospective Studies SARS-CoV-2 - pathogenicity Stroke - epidemiology Stroke - virology |
| title | Stroke Acute Management and Outcomes During the COVID-19 Outbreak: A Cohort Study From the Madrid Stroke Network |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-02T23%3A39%3A56IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Stroke%20Acute%20Management%20and%20Outcomes%20During%20the%20COVID-19%20Outbreak:%20A%20Cohort%20Study%20From%20the%20Madrid%20Stroke%20Network&rft.jtitle=Stroke%20(1970)&rft.au=Fuentes,%20Blanca&rft.date=2021-02-01&rft.volume=52&rft.issue=2&rft.spage=552&rft.epage=562&rft.pages=552-562&rft.issn=0039-2499&rft.eissn=1524-4628&rft_id=info:doi/10.1161/STROKEAHA.120.031769&rft_dat=%3Cproquest_cross%3E2476129326%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2476129326&rft_id=info:pmid/33406872&rfr_iscdi=true |