Renoprotective effect of GLP-1 receptor agonist, liraglutide, in early-phase diabetic kidney disease in spontaneously diabetic Torii fatty rats

Background The aim of this study is to investigate the renoprotective effect of the GLP-1 receptor agonist, liraglutide, in early-phase diabetic kidney disease (DKD) using an animal model of type 2 diabetes with several metabolic disorders. Methods Male 8-week-old spontaneously diabetic Torii (SDT)...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Clinical and experimental nephrology 2021-04, Vol.25 (4), p.365-375
Hauptverfasser:	Yamada, Shohei, Tanabe, Jun, Ogura, Yuji, Nagai, Yoshio, Sugaya, Takeshi, Ohata, Keiichi, Natsuki, Yasunori, Ichikawa, Daisuke, Watanabe, Shiika, Inoue, Kazuho, Hoshino, Seiko, Kimura, Kenjiro, Shibagaki, Yugo, Kamijo-Ikemori, Atsuko
Format:	Artikel
Sprache:	eng
Schlagworte:	Agonists Albumin Albuminuria - physiopathology Albuminuria - prevention & control Animal models Animals Antidiabetics Autophagy Autophagy - drug effects Biomarkers - blood Blood glucose Blood Glucose - drug effects Blood Glucose - metabolism Blood pressure Blood Pressure - drug effects Body weight Diabetes Diabetes mellitus (non-insulin dependent) Diabetes Mellitus, Type 2 - drug therapy Diabetes Mellitus, Type 2 - metabolism Diabetes Mellitus, Type 2 - physiopathology Diabetic Nephropathies - metabolism Diabetic Nephropathies - pathology Diabetic Nephropathies - physiopathology Diabetic Nephropathies - prevention & control Diabetic nephropathy Disease Models, Animal Fatty acid-binding protein Food intake GLP-1 receptor agonists Glucagon-Like Peptide-1 Receptor - agonists Glucagon-Like Peptide-1 Receptor - metabolism Glucose Hyperglycemia Hyperlipidemia Hypertension Hypoglycemic Agents - pharmacology Incretins - pharmacology Insulin Kidney - drug effects Kidney - metabolism Kidney - pathology Kidney - physiopathology Kidney diseases Liraglutide - pharmacology Male Medicine Medicine & Public Health Metabolic disorders Nephrology Original Article Phagocytosis Rats Rats, Inbred Strains Sclerosis Signal Transduction TOR protein Urology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!