Research advances in hydrogen–deuterium exchange mass spectrometry for protein epitope mapping

With the development of biomedical technology, epitope mapping of proteins has become critical for developing and evaluating new protein drugs. The application of hydrogen–deuterium exchange for protein epitope mapping holds great potential. Although several reviews addressed the hydrogen–deuterium...

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Veröffentlicht in:	Analytical and bioanalytical chemistry 2021-04, Vol.413 (9), p.2345-2359
Hauptverfasser:	Sun, Haofeng, Ma, Lingyun, Wang, Leyu, Xiao, Peng, Li, Hongmei, Zhou, Min, Song, Dewei
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical Chemistry Antibodies Biochemistry Characterization and Evaluation of Materials Chemistry Chemistry and Materials Science Deuterium Drug development Epitope mapping Exchanging Food Science Hydrogen Hydrogen-deuterium exchange Laboratory Medicine Literature reviews Mass spectrometry Mass spectroscopy Medical research Methods Monitoring/Environmental Analysis Peptide mapping Polyclonal antibodies Proteins Review Reviews
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