Photo-induced radical thiol-ene chemistry: a versatile toolbox for peptide-based drug design

While the global market for peptide/protein-based therapeutics is witnessing significant growth, the development of peptide drugs remains challenging due to their low oral bioavailability, poor membrane permeability, and reduced metabolic stability. However, a toolbox of chemical approaches has been...

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Veröffentlicht in:Chemical Society reviews 2021-01, Vol.5 (2), p.898-944
Hauptverfasser: Ahangarpour, Marzieh, Kavianinia, Iman, Harris, Paul W. R, Brimble, Margaret A
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Sprache:eng
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