Recent advances in design of antimicrobial peptides and polypeptides toward clinical translation

The recent outbreaks of infectious diseases caused by multidrug-resistant pathogens have sounded a piercing alarm for the need of new effective antimicrobial agents to guard public health. Among different types of candidates, antimicrobial peptides (AMPs) and the synthetic mimics of AMPs (SMAMPs) ha...

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Veröffentlicht in:	Advanced drug delivery reviews 2021-03, Vol.170, p.261-280
Hauptverfasser:	Jiang, Yunjiang, Chen, Yingying, Song, Ziyuan, Tan, Zhengzhong, Cheng, Jianjun
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotic resistance Antimicrobial peptides Clinical translation Combination therapy Infection-responsive peptides Membrane-active antimicrobial mechanism Nano-antimicrobials Radially amphiphilic conformation Small synthetic mimics of antimicrobial peptides
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