Seeking an Initial-Weight-Independent Metric in a Mediterranean Cohort of Gastric Bypass Patients: the %AWL Revisited
Background Most relative weight-loss metrics follow the formula “Weight loss(%) = 100 · (Initial BMI - Final BMI) / (Initial BMI- a ),” where a is the reference point that defines the metric. The percentage of total weight loss (%TWL, a = 0) and percentage of excess weight loss (%EWL, a = 25) are...
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| Veröffentlicht in: | Obesity surgery 2021-04, Vol.31 (4), p.1524-1532 |
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| creator | Beisani, Marc Sabench Pereferrer, Fàtima Vilallonga, Ramón González López, Óscar Molina López, Alicia del Castillo Dejardin, Daniel García Ruiz de Gordejuela, Amador Fort López-Barajas, José Manuel Armengol Carrasco, Manel |
| description | Background
Most relative weight-loss metrics follow the formula “Weight loss(%) = 100 · (Initial BMI - Final BMI) / (Initial BMI-
a
),” where
a
is the reference point that defines the metric. The percentage of total weight loss (%TWL,
a
= 0) and percentage of excess weight loss (%EWL,
a
= 25) are influenced by a patient’s initial weight. Recently, the percentage of alterable weight loss metric (%AWL,
a
= 13) has been reported to produce initial-weight-independent outcomes.
Objectives
This study aimed to replicate the methodology used for %AWL determination in a Mediterranean cohort of bariatric patients.
Settings
Multicenter study in 10 large hospitals in Spain.
Methods
Two large prospective databases were retrospectively searched for all primary laparoscopic gastric bypass patients with 2 years of follow-up. Outcomes at nadir were expressed and analyzed with 26 different metrics (
a
from 0 to 25), looking for the metric whose outcomes produced (1) the lowest coefficient of variation, (2) no differences between initially lighter and heavier patients, and (3) no correlation with patients’ initial BMI.
Results
A cohort of 1793 patients was stratified into 4 gender-age groups: younger women (YW,
n
= 733), older women (OW,
n
= 674), younger men (YM,
n
= 197), and older men (OM,
n
= 189). The calculations suggested an optimal reference point of 18 kg/m
2
, defining a new metric (percentage of Mediterranean alterable weight loss, %MAWL). When %TWL, %EWL, %AWL, and %MAWL were tested on the whole sample, only %MAWL produced initial-weight-independent results.
Conclusions
In our Mediterranean cohort of patients, a reference point of 18 (and not 13) yielded initial-weight-independent outcomes. |
| doi_str_mv | 10.1007/s11695-020-05154-3 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2475401654</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2475401654</sourcerecordid><originalsourceid>FETCH-LOGICAL-c375t-a97e43d6c79fb5808209d4003fae803b47753285735cc6f02c5903eeb5a887263</originalsourceid><addsrcrecordid>eNp9kV1rFDEUhoModq3-AS8kIII30ZOvSeJdXbQubFH8oJchO3NmN3V3ZptkCv33pt3WghfeJIE8z3sOvIS85PCOA5j3mfPGaQYCGGiuFZOPyIwbsAyUsI_JDFwDzDohj8iznC8ABG-EeEqOpJTONkLPyPQD8Xcc1jQMdDHEEsOWnWNcbwpbDB3usR5DoWdYUmxpHGio7y4WTCkMWKX5uBlToWNPT0O-hT5e70PO9Fsosar5Ay0bpG9Ozpf0O17FXN3uOXnSh23GF3f3Mfn1-dPP-Re2_Hq6mJ8sWSuNLiw4g0p2TWtcv9IWrADXKQDZB7QgV8oYLYXVRuq2bXoQrXYgEVc6WGtEI4_J20PuPo2XE-bidzG3uN3W3ccpe6GMVsAbrSr6-h_0YpzSULfzQoORjXLuhhIHqk1jzgl7v09xF9K15-BvSvGHUnwtxd-W4mWVXt1FT6sddn-V-xYqIA9Arl_DGtPD7P_E_gHyZpWj</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2507364994</pqid></control><display><type>article</type><title>Seeking an Initial-Weight-Independent Metric in a Mediterranean Cohort of Gastric Bypass Patients: the %AWL Revisited</title><source>MEDLINE</source><source>SpringerLink Journals - AutoHoldings</source><creator>Beisani, Marc ; Sabench Pereferrer, Fàtima ; Vilallonga, Ramón ; González López, Óscar ; Molina López, Alicia ; del Castillo Dejardin, Daniel ; García Ruiz de Gordejuela, Amador ; Fort López-Barajas, José Manuel ; Armengol Carrasco, Manel</creator><creatorcontrib>Beisani, Marc ; Sabench Pereferrer, Fàtima ; Vilallonga, Ramón ; González López, Óscar ; Molina López, Alicia ; del Castillo Dejardin, Daniel ; García Ruiz de Gordejuela, Amador ; Fort López-Barajas, José Manuel ; Armengol Carrasco, Manel ; Members of the Obesity Section of the Spanish Surgical Association Collaborative Group ; Members of the Obesity Section of the Spanish Surgical Association Collaborative Group</creatorcontrib><description>Background
Most relative weight-loss metrics follow the formula “Weight loss(%) = 100 · (Initial BMI - Final BMI) / (Initial BMI-
a
),” where
a
is the reference point that defines the metric. The percentage of total weight loss (%TWL,
a
= 0) and percentage of excess weight loss (%EWL,
a
= 25) are influenced by a patient’s initial weight. Recently, the percentage of alterable weight loss metric (%AWL,
a
= 13) has been reported to produce initial-weight-independent outcomes.
Objectives
This study aimed to replicate the methodology used for %AWL determination in a Mediterranean cohort of bariatric patients.
Settings
Multicenter study in 10 large hospitals in Spain.
Methods
Two large prospective databases were retrospectively searched for all primary laparoscopic gastric bypass patients with 2 years of follow-up. Outcomes at nadir were expressed and analyzed with 26 different metrics (
a
from 0 to 25), looking for the metric whose outcomes produced (1) the lowest coefficient of variation, (2) no differences between initially lighter and heavier patients, and (3) no correlation with patients’ initial BMI.
Results
A cohort of 1793 patients was stratified into 4 gender-age groups: younger women (YW,
n
= 733), older women (OW,
n
= 674), younger men (YM,
n
= 197), and older men (OM,
n
= 189). The calculations suggested an optimal reference point of 18 kg/m
2
, defining a new metric (percentage of Mediterranean alterable weight loss, %MAWL). When %TWL, %EWL, %AWL, and %MAWL were tested on the whole sample, only %MAWL produced initial-weight-independent results.
Conclusions
In our Mediterranean cohort of patients, a reference point of 18 (and not 13) yielded initial-weight-independent outcomes.</description><identifier>ISSN: 0960-8923</identifier><identifier>EISSN: 1708-0428</identifier><identifier>DOI: 10.1007/s11695-020-05154-3</identifier><identifier>PMID: 33398625</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Aged ; Body Mass Index ; Female ; Gastric Bypass ; Gastrointestinal surgery ; Humans ; Laparoscopy ; Male ; Medicine ; Medicine & Public Health ; Obesity, Morbid - surgery ; Original Contributions ; Retrospective Studies ; Spain - epidemiology ; Surgery ; Treatment Outcome</subject><ispartof>Obesity surgery, 2021-04, Vol.31 (4), p.1524-1532</ispartof><rights>The Author(s), under exclusive licence to Springer Science+Business Media, LLC part of Springer Nature 2021</rights><rights>The Author(s), under exclusive licence to Springer Science+Business Media, LLC part of Springer Nature 2021.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c375t-a97e43d6c79fb5808209d4003fae803b47753285735cc6f02c5903eeb5a887263</citedby><cites>FETCH-LOGICAL-c375t-a97e43d6c79fb5808209d4003fae803b47753285735cc6f02c5903eeb5a887263</cites><orcidid>0000-0002-0485-8536</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11695-020-05154-3$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s11695-020-05154-3$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>315,781,785,27926,27927,41490,42559,51321</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33398625$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Beisani, Marc</creatorcontrib><creatorcontrib>Sabench Pereferrer, Fàtima</creatorcontrib><creatorcontrib>Vilallonga, Ramón</creatorcontrib><creatorcontrib>González López, Óscar</creatorcontrib><creatorcontrib>Molina López, Alicia</creatorcontrib><creatorcontrib>del Castillo Dejardin, Daniel</creatorcontrib><creatorcontrib>García Ruiz de Gordejuela, Amador</creatorcontrib><creatorcontrib>Fort López-Barajas, José Manuel</creatorcontrib><creatorcontrib>Armengol Carrasco, Manel</creatorcontrib><creatorcontrib>Members of the Obesity Section of the Spanish Surgical Association Collaborative Group</creatorcontrib><creatorcontrib>Members of the Obesity Section of the Spanish Surgical Association Collaborative Group</creatorcontrib><title>Seeking an Initial-Weight-Independent Metric in a Mediterranean Cohort of Gastric Bypass Patients: the %AWL Revisited</title><title>Obesity surgery</title><addtitle>OBES SURG</addtitle><addtitle>Obes Surg</addtitle><description>Background
Most relative weight-loss metrics follow the formula “Weight loss(%) = 100 · (Initial BMI - Final BMI) / (Initial BMI-
a
),” where
a
is the reference point that defines the metric. The percentage of total weight loss (%TWL,
a
= 0) and percentage of excess weight loss (%EWL,
a
= 25) are influenced by a patient’s initial weight. Recently, the percentage of alterable weight loss metric (%AWL,
a
= 13) has been reported to produce initial-weight-independent outcomes.
Objectives
This study aimed to replicate the methodology used for %AWL determination in a Mediterranean cohort of bariatric patients.
Settings
Multicenter study in 10 large hospitals in Spain.
Methods
Two large prospective databases were retrospectively searched for all primary laparoscopic gastric bypass patients with 2 years of follow-up. Outcomes at nadir were expressed and analyzed with 26 different metrics (
a
from 0 to 25), looking for the metric whose outcomes produced (1) the lowest coefficient of variation, (2) no differences between initially lighter and heavier patients, and (3) no correlation with patients’ initial BMI.
Results
A cohort of 1793 patients was stratified into 4 gender-age groups: younger women (YW,
n
= 733), older women (OW,
n
= 674), younger men (YM,
n
= 197), and older men (OM,
n
= 189). The calculations suggested an optimal reference point of 18 kg/m
2
, defining a new metric (percentage of Mediterranean alterable weight loss, %MAWL). When %TWL, %EWL, %AWL, and %MAWL were tested on the whole sample, only %MAWL produced initial-weight-independent results.
Conclusions
In our Mediterranean cohort of patients, a reference point of 18 (and not 13) yielded initial-weight-independent outcomes.</description><subject>Aged</subject><subject>Body Mass Index</subject><subject>Female</subject><subject>Gastric Bypass</subject><subject>Gastrointestinal surgery</subject><subject>Humans</subject><subject>Laparoscopy</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Obesity, Morbid - surgery</subject><subject>Original Contributions</subject><subject>Retrospective Studies</subject><subject>Spain - epidemiology</subject><subject>Surgery</subject><subject>Treatment Outcome</subject><issn>0960-8923</issn><issn>1708-0428</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp9kV1rFDEUhoModq3-AS8kIII30ZOvSeJdXbQubFH8oJchO3NmN3V3ZptkCv33pt3WghfeJIE8z3sOvIS85PCOA5j3mfPGaQYCGGiuFZOPyIwbsAyUsI_JDFwDzDohj8iznC8ABG-EeEqOpJTONkLPyPQD8Xcc1jQMdDHEEsOWnWNcbwpbDB3usR5DoWdYUmxpHGio7y4WTCkMWKX5uBlToWNPT0O-hT5e70PO9Fsosar5Ay0bpG9Ozpf0O17FXN3uOXnSh23GF3f3Mfn1-dPP-Re2_Hq6mJ8sWSuNLiw4g0p2TWtcv9IWrADXKQDZB7QgV8oYLYXVRuq2bXoQrXYgEVc6WGtEI4_J20PuPo2XE-bidzG3uN3W3ccpe6GMVsAbrSr6-h_0YpzSULfzQoORjXLuhhIHqk1jzgl7v09xF9K15-BvSvGHUnwtxd-W4mWVXt1FT6sddn-V-xYqIA9Arl_DGtPD7P_E_gHyZpWj</recordid><startdate>20210401</startdate><enddate>20210401</enddate><creator>Beisani, Marc</creator><creator>Sabench Pereferrer, Fàtima</creator><creator>Vilallonga, Ramón</creator><creator>González López, Óscar</creator><creator>Molina López, Alicia</creator><creator>del Castillo Dejardin, Daniel</creator><creator>García Ruiz de Gordejuela, Amador</creator><creator>Fort López-Barajas, José Manuel</creator><creator>Armengol Carrasco, Manel</creator><general>Springer US</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-0485-8536</orcidid></search><sort><creationdate>20210401</creationdate><title>Seeking an Initial-Weight-Independent Metric in a Mediterranean Cohort of Gastric Bypass Patients: the %AWL Revisited</title><author>Beisani, Marc ; Sabench Pereferrer, Fàtima ; Vilallonga, Ramón ; González López, Óscar ; Molina López, Alicia ; del Castillo Dejardin, Daniel ; García Ruiz de Gordejuela, Amador ; Fort López-Barajas, José Manuel ; Armengol Carrasco, Manel</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c375t-a97e43d6c79fb5808209d4003fae803b47753285735cc6f02c5903eeb5a887263</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Aged</topic><topic>Body Mass Index</topic><topic>Female</topic><topic>Gastric Bypass</topic><topic>Gastrointestinal surgery</topic><topic>Humans</topic><topic>Laparoscopy</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Obesity, Morbid - surgery</topic><topic>Original Contributions</topic><topic>Retrospective Studies</topic><topic>Spain - epidemiology</topic><topic>Surgery</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Beisani, Marc</creatorcontrib><creatorcontrib>Sabench Pereferrer, Fàtima</creatorcontrib><creatorcontrib>Vilallonga, Ramón</creatorcontrib><creatorcontrib>González López, Óscar</creatorcontrib><creatorcontrib>Molina López, Alicia</creatorcontrib><creatorcontrib>del Castillo Dejardin, Daniel</creatorcontrib><creatorcontrib>García Ruiz de Gordejuela, Amador</creatorcontrib><creatorcontrib>Fort López-Barajas, José Manuel</creatorcontrib><creatorcontrib>Armengol Carrasco, Manel</creatorcontrib><creatorcontrib>Members of the Obesity Section of the Spanish Surgical Association Collaborative Group</creatorcontrib><creatorcontrib>Members of the Obesity Section of the Spanish Surgical Association Collaborative Group</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Obesity surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Beisani, Marc</au><au>Sabench Pereferrer, Fàtima</au><au>Vilallonga, Ramón</au><au>González López, Óscar</au><au>Molina López, Alicia</au><au>del Castillo Dejardin, Daniel</au><au>García Ruiz de Gordejuela, Amador</au><au>Fort López-Barajas, José Manuel</au><au>Armengol Carrasco, Manel</au><aucorp>Members of the Obesity Section of the Spanish Surgical Association Collaborative Group</aucorp><aucorp>Members of the Obesity Section of the Spanish Surgical Association Collaborative Group</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Seeking an Initial-Weight-Independent Metric in a Mediterranean Cohort of Gastric Bypass Patients: the %AWL Revisited</atitle><jtitle>Obesity surgery</jtitle><stitle>OBES SURG</stitle><addtitle>Obes Surg</addtitle><date>2021-04-01</date><risdate>2021</risdate><volume>31</volume><issue>4</issue><spage>1524</spage><epage>1532</epage><pages>1524-1532</pages><issn>0960-8923</issn><eissn>1708-0428</eissn><abstract>Background
Most relative weight-loss metrics follow the formula “Weight loss(%) = 100 · (Initial BMI - Final BMI) / (Initial BMI-
a
),” where
a
is the reference point that defines the metric. The percentage of total weight loss (%TWL,
a
= 0) and percentage of excess weight loss (%EWL,
a
= 25) are influenced by a patient’s initial weight. Recently, the percentage of alterable weight loss metric (%AWL,
a
= 13) has been reported to produce initial-weight-independent outcomes.
Objectives
This study aimed to replicate the methodology used for %AWL determination in a Mediterranean cohort of bariatric patients.
Settings
Multicenter study in 10 large hospitals in Spain.
Methods
Two large prospective databases were retrospectively searched for all primary laparoscopic gastric bypass patients with 2 years of follow-up. Outcomes at nadir were expressed and analyzed with 26 different metrics (
a
from 0 to 25), looking for the metric whose outcomes produced (1) the lowest coefficient of variation, (2) no differences between initially lighter and heavier patients, and (3) no correlation with patients’ initial BMI.
Results
A cohort of 1793 patients was stratified into 4 gender-age groups: younger women (YW,
n
= 733), older women (OW,
n
= 674), younger men (YM,
n
= 197), and older men (OM,
n
= 189). The calculations suggested an optimal reference point of 18 kg/m
2
, defining a new metric (percentage of Mediterranean alterable weight loss, %MAWL). When %TWL, %EWL, %AWL, and %MAWL were tested on the whole sample, only %MAWL produced initial-weight-independent results.
Conclusions
In our Mediterranean cohort of patients, a reference point of 18 (and not 13) yielded initial-weight-independent outcomes.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>33398625</pmid><doi>10.1007/s11695-020-05154-3</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0002-0485-8536</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0960-8923 |
| ispartof | Obesity surgery, 2021-04, Vol.31 (4), p.1524-1532 |
| issn | 0960-8923 1708-0428 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2475401654 |
| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Aged Body Mass Index Female Gastric Bypass Gastrointestinal surgery Humans Laparoscopy Male Medicine Medicine & Public Health Obesity, Morbid - surgery Original Contributions Retrospective Studies Spain - epidemiology Surgery Treatment Outcome |
| title | Seeking an Initial-Weight-Independent Metric in a Mediterranean Cohort of Gastric Bypass Patients: the %AWL Revisited |
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