Human adipose‐derived stromal/stem cells are distinct from dermal fibroblasts as evaluated by biological characterization and RNA sequencing

Human adipose‐derived stromal/stem cells (ASC) have immunomodulatory properties and the potential to differentiate into several cell lines, important for application in regenerative medicine. However, the contamination with dermal fibroblasts (FIB) can impair the beneficial effects of ASC in cell th...

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Veröffentlicht in:	Cell biochemistry and function 2021-04, Vol.39 (3), p.442-454
Hauptverfasser:	Melo, Mariane Izabella, Cunha, Pricila, de Miranda, Marcelo, Faraco, Camila Cristina Fraga, Barbosa, Joana Lobato, Ferreira, Andrea, Kunrath Lima, Marianna, Faria, Jerusa Araújo Quintão Arantes, Rodrigues, Michele Ângela, Goes, Alfredo Miranda, Gomes, Dawidson Assis
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose tissue Alkaline phosphatase Biological properties Biomarkers Biomedical materials Cell cycle Cell differentiation Cell lines Cell therapy Contamination Differentiation (biology) Extracellular matrix Fibroblasts Gene expression Gene sequencing Genes human adipose‐derived stromal/stem cells human dermal fibroblasts Immunomodulation phenotypic characterization Phosphatase Populations Regenerative medicine Ribonucleic acid RNA RNA sequencing Skin Stem cells Tissue engineering
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