Tuning multilayered polymeric self-standing films for controlled release of L-lactate by electrical stimulation

We examine different approaches for the controlled release of L-lactate, which is a signaling molecule that participates in tissue remodeling and regeneration, such as cardiac and muscle tissue. Robust, flexible, and self-supported 3-layers films made of two spin-coated poly(lactic acid) (PLA) layer...

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Veröffentlicht in:	Journal of controlled release 2021-02, Vol.330, p.669-683
Hauptverfasser:	Puiggalí-Jou, Anna, Ordoño, Jesús, del Valle, Luis J., Pérez-Amodio, Soledad, Engel, Elisabeth, Alemán, Carlos
Format:	Artikel
Sprache:	eng
Schlagworte:	Biphasic voltage pulse Cardiac tissue regeneration Cardiomyocytes proliferation Conducting polymer Nanoperforated films Sustained delivery
Online-Zugang:	Volltext
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