Analysis of Target Molecules towards Anti-cancer Therapeutic Antibodies

Target molecules of existing anti-cancer therapeutic monoclonal antibodies (mAbs) are divided into 1) receptor-type tyrosine kinases, such as human epidermal growth factor receptor (HER) family, 2) differentiation antigens, such as CD20 (Rituxan target), 3) angiogenesis-related molecules, and 4) imm...

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Veröffentlicht in:	YAKUGAKU ZASSHI 2021/01/01, Vol.141(1), pp.81-92
1. Verfasser:	Masuko, Takashi
Format:	Artikel
Sprache:	eng ; jpn
Schlagworte:	Animals Antibodies, Monoclonal - therapeutic use antigen analysis Antigens, CD20 cancer therapy Humans Membrane Transport Proteins Mice Molecular Targeted Therapy monoclonal antibody Neoplasms - drug therapy Neoplasms - genetics Oncogene Proteins Programmed Cell Death 1 Receptor Rats Receptor, ErbB-2 Rituximab Vesicular Transport Proteins
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