6‐Nitro‐Quinazolin−4(3H)−one Exhibits Photodynamic Effects and Photodegrades Human Melanoma Cell Lines. A Study on the Photoreactivity of Simple Quinazolin−4(3H)−ones

Photochemo and photodynamic therapies are minimally invasive approaches for the treatment of cancers and powerful weapons for competing bacterial resistance to antibiotics. Synthetic and naturally occurring quinazolinones are considered privileged anticancer and antibacterial agents, with several of...

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Veröffentlicht in:	Photochemistry and photobiology 2021-07, Vol.97 (4), p.826-836
Hauptverfasser:	Panagopoulos, Anastasios, Balalas, Thomas, Mitrakas, Achilleas, Vrazas, Vassilios, Katsani, Katerina R., Koumbis, Alexandros E., Koukourakis, Michael I., Litinas, Konstantinos E., Fylaktakidou, Konstantina C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - pharmacology Antibacterial agents Antibiotics Anticancer properties Antiinfectives and antibacterials Biotechnology Cell Line Cell lines Deoxyribonucleic acid DNA Glioblastoma Humans Irradiation Low concentrations Melanoma Plasmids Quinazolinone Quinazolinones Quinazolinones - pharmacology Reactive oxygen species Structure-Activity Relationship Ultraviolet radiation
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