Clinical features and laboratory characteristics of patients hospitalized with COVID-19: single centre report from Egypt
The recently discovered novel coronavirus disease (COVID-19) has emerged in Wuhan, China, since January 2020. Egypt reported a low incidence of infection when compared with other countries. The aim of the study was to assess the characterization of COVID-19 infection among the Egyptian population. D...
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| Veröffentlicht in: | Journal of infection in developing countries 2020-12, Vol.14 (12), p.1352-1360 |
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| creator | El Kassas, Mohamed Asem, Noha Abdelazeem, Amr Madkour, Ahmad Sayed, Hamdy Tawheed, Ahmed Al Shafie, Ahmed Gamal, Mahmoud Elsayed, Hassan Badr, Mohamed Hassany, Mohamed Omran, Dalia El Fouly, Amr |
| description | The recently discovered novel coronavirus disease (COVID-19) has emerged in Wuhan, China, since January 2020. Egypt reported a low incidence of infection when compared with other countries. The aim of the study was to assess the characterization of COVID-19 infection among the Egyptian population.
Data were collected from a single COVID-19 quarantine hospital in Cairo. A total number of 195 cases were included with their clinical, laboratory, and radiological data.
Three different age groups behaved differently for COVD-19 infection. The pediatric age group was asymptomatic entirely, the middle age group (18-50 years) were asymptomatic in 53.3% of cases, while 77.9% of those above 50 years were symptomatic (p ≤ 0.001). The latter group had a high incidence of COVID-pneumonia in (83.1%), and moderate to critical presentations were encountered in 66.3% of them. Neutrophil to lymphocyte (N/L) ratio correlated directly with the age and case severity. C-reactive protein (CRP) and computed tomography scan chest (CT-chest) had added value on COVID-19 diagnosis in suspected cases.
In Egypt, patients above 50 years are at a higher risk for symptomatic COVID-19 infection and leaner for moderate to critical COVID-19 presentation. The triad of CT-chest, CRP, and N/L ratio could be an integrated panel for assessing disease severity. |
| doi_str_mv | 10.3855/jidc.13156 |
| format | Article |
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Data were collected from a single COVID-19 quarantine hospital in Cairo. A total number of 195 cases were included with their clinical, laboratory, and radiological data.
Three different age groups behaved differently for COVD-19 infection. The pediatric age group was asymptomatic entirely, the middle age group (18-50 years) were asymptomatic in 53.3% of cases, while 77.9% of those above 50 years were symptomatic (p ≤ 0.001). The latter group had a high incidence of COVID-pneumonia in (83.1%), and moderate to critical presentations were encountered in 66.3% of them. Neutrophil to lymphocyte (N/L) ratio correlated directly with the age and case severity. C-reactive protein (CRP) and computed tomography scan chest (CT-chest) had added value on COVID-19 diagnosis in suspected cases.
In Egypt, patients above 50 years are at a higher risk for symptomatic COVID-19 infection and leaner for moderate to critical COVID-19 presentation. The triad of CT-chest, CRP, and N/L ratio could be an integrated panel for assessing disease severity.</description><identifier>ISSN: 1972-2680</identifier><identifier>ISSN: 2036-6590</identifier><identifier>EISSN: 1972-2680</identifier><identifier>DOI: 10.3855/jidc.13156</identifier><identifier>PMID: 33378275</identifier><language>eng</language><publisher>Italy: Journal of Infection in Developing Countries</publisher><subject>Adolescent ; Adult ; Age Factors ; Age groups ; Asymptomatic ; Asymptomatic Infections - epidemiology ; Child ; Coronaviruses ; COVID-19 ; COVID-19 - diagnostic imaging ; COVID-19 - epidemiology ; COVID-19 - physiopathology ; Egypt - epidemiology ; Female ; Hospitalization ; Humans ; Infections ; Laboratories ; Lymphocytes - cytology ; Male ; Middle Aged ; Neutrophils - cytology ; Retrospective Studies ; Risk Factors ; Severity of Illness Index ; Tomography, X-Ray Computed ; Young Adult</subject><ispartof>Journal of infection in developing countries, 2020-12, Vol.14 (12), p.1352-1360</ispartof><rights>Copyright (c) 2020 Mohamed El Kassas, Noha Asem, Amr Abdelazeem, Ahmad Madkour, Hamdy Sayed, Ahmed Tawheed, Ahmed Al Shafie, Mahmoud Gamal, Hassan Elsayed, Mohamed Badr, Mohamed Hassany, Dalia Omran, Amr El Fouly.</rights><rights>2020. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c315t-e98b6efd43df84bbaa591e70f1fa67ba12eefd3189fea3768fc41a14f1158a9f3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33378275$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>El Kassas, Mohamed</creatorcontrib><creatorcontrib>Asem, Noha</creatorcontrib><creatorcontrib>Abdelazeem, Amr</creatorcontrib><creatorcontrib>Madkour, Ahmad</creatorcontrib><creatorcontrib>Sayed, Hamdy</creatorcontrib><creatorcontrib>Tawheed, Ahmed</creatorcontrib><creatorcontrib>Al Shafie, Ahmed</creatorcontrib><creatorcontrib>Gamal, Mahmoud</creatorcontrib><creatorcontrib>Elsayed, Hassan</creatorcontrib><creatorcontrib>Badr, Mohamed</creatorcontrib><creatorcontrib>Hassany, Mohamed</creatorcontrib><creatorcontrib>Omran, Dalia</creatorcontrib><creatorcontrib>El Fouly, Amr</creatorcontrib><title>Clinical features and laboratory characteristics of patients hospitalized with COVID-19: single centre report from Egypt</title><title>Journal of infection in developing countries</title><addtitle>J Infect Dev Ctries</addtitle><description>The recently discovered novel coronavirus disease (COVID-19) has emerged in Wuhan, China, since January 2020. Egypt reported a low incidence of infection when compared with other countries. The aim of the study was to assess the characterization of COVID-19 infection among the Egyptian population.
Data were collected from a single COVID-19 quarantine hospital in Cairo. A total number of 195 cases were included with their clinical, laboratory, and radiological data.
Three different age groups behaved differently for COVD-19 infection. The pediatric age group was asymptomatic entirely, the middle age group (18-50 years) were asymptomatic in 53.3% of cases, while 77.9% of those above 50 years were symptomatic (p ≤ 0.001). The latter group had a high incidence of COVID-pneumonia in (83.1%), and moderate to critical presentations were encountered in 66.3% of them. Neutrophil to lymphocyte (N/L) ratio correlated directly with the age and case severity. C-reactive protein (CRP) and computed tomography scan chest (CT-chest) had added value on COVID-19 diagnosis in suspected cases.
In Egypt, patients above 50 years are at a higher risk for symptomatic COVID-19 infection and leaner for moderate to critical COVID-19 presentation. The triad of CT-chest, CRP, and N/L ratio could be an integrated panel for assessing disease severity.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Age Factors</subject><subject>Age groups</subject><subject>Asymptomatic</subject><subject>Asymptomatic Infections - epidemiology</subject><subject>Child</subject><subject>Coronaviruses</subject><subject>COVID-19</subject><subject>COVID-19 - diagnostic imaging</subject><subject>COVID-19 - epidemiology</subject><subject>COVID-19 - physiopathology</subject><subject>Egypt - epidemiology</subject><subject>Female</subject><subject>Hospitalization</subject><subject>Humans</subject><subject>Infections</subject><subject>Laboratories</subject><subject>Lymphocytes - cytology</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Neutrophils - cytology</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Severity of Illness Index</subject><subject>Tomography, X-Ray Computed</subject><subject>Young Adult</subject><issn>1972-2680</issn><issn>2036-6590</issn><issn>1972-2680</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNpdkU1r3DAQhkVpaL56yQ8ogl5CwInGsmy5t7JJ20Agl7ZXM5ZHWS1ey5Vkmu2vj_JVSk8zMA8v7_AwdgLiXGqlLjZuMOcgQdVv2AG0TVmUtRZv_9n32WGMGyFUKxW8Y_tSykaXjTpg96vRTc7gyC1hWgJFjtPAR-x9wOTDjps1BjSJgovJmci95TMmR1OKfO3j7BKO7g8N_LdLa766_Xl9WUD7iUc33Y3ETQYD8UCzD4nb4Lf86m43p2O2Z3GM9P5lHrEfX66-r74VN7dfr1efbwqTH0oFtbqvyQ6VHKyu-h5RtUCNsGCxbnqEkvJVgm5zf9nU2poKECoLoDS2Vh6x0-fcOfhfC8XUbV00NI44kV9iV1ZNVbW6LCGjH_9DN34JU27XlaoWIEQGM3X2TJngYwxkuzm4LYZdB6J79NE9-uiefGT4w0vk0m9p-Iu-CpAPXIqH6g</recordid><startdate>20201231</startdate><enddate>20201231</enddate><creator>El Kassas, Mohamed</creator><creator>Asem, Noha</creator><creator>Abdelazeem, Amr</creator><creator>Madkour, Ahmad</creator><creator>Sayed, Hamdy</creator><creator>Tawheed, Ahmed</creator><creator>Al Shafie, Ahmed</creator><creator>Gamal, Mahmoud</creator><creator>Elsayed, Hassan</creator><creator>Badr, Mohamed</creator><creator>Hassany, Mohamed</creator><creator>Omran, Dalia</creator><creator>El Fouly, Amr</creator><general>Journal of Infection in Developing Countries</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8C1</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>COVID</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20201231</creationdate><title>Clinical features and laboratory characteristics of patients hospitalized with COVID-19: single centre report from Egypt</title><author>El Kassas, Mohamed ; 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Egypt reported a low incidence of infection when compared with other countries. The aim of the study was to assess the characterization of COVID-19 infection among the Egyptian population.
Data were collected from a single COVID-19 quarantine hospital in Cairo. A total number of 195 cases were included with their clinical, laboratory, and radiological data.
Three different age groups behaved differently for COVD-19 infection. The pediatric age group was asymptomatic entirely, the middle age group (18-50 years) were asymptomatic in 53.3% of cases, while 77.9% of those above 50 years were symptomatic (p ≤ 0.001). The latter group had a high incidence of COVID-pneumonia in (83.1%), and moderate to critical presentations were encountered in 66.3% of them. Neutrophil to lymphocyte (N/L) ratio correlated directly with the age and case severity. C-reactive protein (CRP) and computed tomography scan chest (CT-chest) had added value on COVID-19 diagnosis in suspected cases.
In Egypt, patients above 50 years are at a higher risk for symptomatic COVID-19 infection and leaner for moderate to critical COVID-19 presentation. The triad of CT-chest, CRP, and N/L ratio could be an integrated panel for assessing disease severity.</abstract><cop>Italy</cop><pub>Journal of Infection in Developing Countries</pub><pmid>33378275</pmid><doi>10.3855/jidc.13156</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 1972-2680 |
| ispartof | Journal of infection in developing countries, 2020-12, Vol.14 (12), p.1352-1360 |
| issn | 1972-2680 2036-6590 1972-2680 |
| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Adolescent Adult Age Factors Age groups Asymptomatic Asymptomatic Infections - epidemiology Child Coronaviruses COVID-19 COVID-19 - diagnostic imaging COVID-19 - epidemiology COVID-19 - physiopathology Egypt - epidemiology Female Hospitalization Humans Infections Laboratories Lymphocytes - cytology Male Middle Aged Neutrophils - cytology Retrospective Studies Risk Factors Severity of Illness Index Tomography, X-Ray Computed Young Adult |
| title | Clinical features and laboratory characteristics of patients hospitalized with COVID-19: single centre report from Egypt |
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