Third‐party bone marrow–derived mesenchymal stromal cell infusion before liver transplantation: A randomized controlled trial

Mesenchymal stromal cells (MSC) have emerged as a promising therapy to minimize the immunosuppressive regimen or induce tolerance in solid organ transplantation. In this randomized open‐label phase Ib/IIa clinical trial, 20 liver transplant patients were randomly allocated (1:1) to receive a single...

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Veröffentlicht in:	American journal of transplantation 2021-08, Vol.21 (8), p.2795-2809
Hauptverfasser:	Casiraghi, Federica, Perico, Norberto, Podestà, Manuel A., Todeschini, Marta, Zambelli, Marco, Colledan, Michele, Camagni, Stefania, Fagiuoli, Stefano, Pinna, Antonio D., Cescon, Matteo, Bertuzzo, Valentina, Maroni, Lorenzo, Introna, Martino, Capelli, Chiara, Golay, Josee T., Buzzi, Marina, Mister, Marilena, Ordonez, Pamela Y. R., Breno, Matteo, Mele, Caterina, Villa, Alessandro, Remuzzi, Giuseppe, Zambelli, Marco F., Magini, Giulia, Baldan, Anna, Lucà, Maria G., Rota, Loredana, Ravaioli, Matteo, Morelli, Mariacristina, Pedrini, Olga, Manara, Sabrina, Morara, Barbara, Rubis, Nadia, Diadei, Olimpia, Martinetti, Davide, Carminati, Sergio, Giuliano, Giovanni A., Boccardo, Paola, Peracchi, Sara
Format:	Artikel
Sprache:	eng
Schlagworte:	Adverse events Bone Marrow Bone marrow transplantation clinical research/practice Clinical trials Hepatocytes Humans Immunological tolerance Immunoregulation Immunosuppressive Agents Intravenous administration Liver Transplantation liver transplantation/hepatology Liver transplants Lymphocytes T Mesenchymal Stem Cell Transplantation Mesenchymal Stem Cells Mesenchyme Patients Peripheral blood Statistical analysis stem cells Stromal cells tolerance
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