An exacerbated metabolism and mitochondrial reactive oxygen species contribute to mitochondrial alterations and apoptosis in CD4 T cells during the acute phase of Trypanosoma cruzi infection

Chagas disease caused by Trypanosoma cruzi parasite is an endemic infection in America. It is well known that T. cruzi causes a strong immunosuppression during the acute phase of infection. However, it is not clear whether T. cruzi infection is related to metabolic alterations in CD4 T cells that pr...

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Veröffentlicht in:	Free radical biology & medicine 2021-02, Vol.163, p.268-280
Hauptverfasser:	Ana, Y., Rojas Marquez, J.D., Fozzatti, L., Baigorrí, R.E., Marin, C., Maletto, B.A., Cerbán, F.M., Radi, R., Piacenza, L., Stempin, C.C.
Format:	Artikel
Sprache:	eng
Schlagworte:	CD4 T cell Metabolism Mitochondria ROS Trypanosoma cruzi
Online-Zugang:	Volltext
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