Mini-review on the properties and possible applications of therapeutic oxygen carrier Hemarina-M101

Therapeutic Oxygen Carriers (TOCs) have been studied in the past for utilization in resuscitation fluid, treatment of organ ischemia, and as an alternative to red blood cell transfusion. One TOC, Hemarina-M101, seems promising in transplantation and oxygenation due its capability as a non-immunogeni...

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Veröffentlicht in:	Transfusion and apheresis science 2021-02, Vol.60 (1), p.103016-103016, Article 103016
Hauptverfasser:	Varney, Joseph, Rivera, Amanda, Dong, Vinh, Tieu, Paul, Zia, Sairah, Huy, Nguyen Tien
Format:	Artikel
Sprache:	eng
Schlagworte:	Arenicola marina Health technology assessment Hemarina-M101 Hemoglobin-based artificial oxygen carriers Therapeutic oxygen carriers TOCs
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Beschreibung
Zusammenfassung:	Therapeutic Oxygen Carriers (TOCs) have been studied in the past for utilization in resuscitation fluid, treatment of organ ischemia, and as an alternative to red blood cell transfusion. One TOC, Hemarina-M101, seems promising in transplantation and oxygenation due its capability as a non-immunogenic, nontoxic, high-oxygen-carrying capacity TOC with little to no side effects. This mini-review focuses on Hemarina-M101 and explores its characteristics and possible utilities through past and recent studies.
ISSN:	1473-0502 1878-1683
DOI:	10.1016/j.transci.2020.103016