Real-time monitoring of caspase-3/8 activity by self-assembling nanofiber probes in living cells

Caspase-3/8 are key members of the cysteine-aspartyl protease family with pivotal roles in apoptosis. We have designed and synthesized self-assembling probes, Nap-GFFpYDEVD-AFC and Nap-GFFpYIETD-AFC, with fluorescence 'turn-on' properties for real-time monitoring of Caspase-3/8 activity in...

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2021-01, Vol.57 (6), p.797-8
Hauptverfasser: Zhang, Li-Song, Xu, Hong-Lei, Xia, Ying, Bi, Jian-Peng, Zhang, Chuan-Zeng, Xi, Zhen, Li, Lu-Yuan, Zhang, Zhi-Song
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Sprache:eng
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