PD1 expression and correlation with its ligands in oral cancer specimens and peripheral blood

This study analyzed the expression of the PD1 receptor in tumor tissue and peripheral blood of oral squamous cell carcinoma (OSCC) patients, and correlated it with the PD1 ligands PD-L1 and PD-L2. The currently low response rates of checkpoint inhibitor treatment in OSCC could be increased by a bett...

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Veröffentlicht in:	Journal of cranio-maxillo-facial surgery 2021-02, Vol.49 (2), p.118-125
Hauptverfasser:	Wehrhan, Falk, Weber, Manuel, Baran, Christoph, Agaimy, Abbas, Büttner-Herold, Maike, Kesting, Marco, Ries, Jutta
Format:	Artikel
Sprache:	eng
Schlagworte:	Carcinoma, Squamous Cell Head and Neck Neoplasms Humans Immune checkpoint Ligands Mouth Neoplasms OSCC PD-L1 PD-L2 PD1 Programmed Cell Death 1 Receptor - metabolism RT-qPCR
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