3α-Angeloyloxy-ent-kaur-16-en-19-oic Acid Isolated from Wedelia trilobata L. Alleviates Xylene-Induced Mouse Ear Edema and Inhibits NF-κB and MAPK Pathway in LPS-Stimulated Macrophages

Uncontrolled inflammation is associated with many major diseases, and there is still an urgent need to develop new anti-inflammatory drugs. 3α-Angeloyloxy-ent-kaur-16-en-19-oic acid (WT-25) is an ent-kaurane dieterpenoid extracted from Wedelia trilobata, a medicinal plant with potential anti-inflamm...

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Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 2020-12, Vol.83 (12), p.3726-3735
Hauptverfasser:	Xu, Jingwen, Zhou, Lei, Sun, Lianlian, Wang, Zhe, Wang, Yi, Wang, Yihai, He, Xiangjiu
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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