Association between thrombotic microangiopathy and activated alternative complement pathway in malignant nephrosclerosis

Malignant nephrosclerosis, defined as renal microangiopathy in the setting of severe hypertension, remains a critical renal emergency leading to end-stage renal disease despite aggressive anti-hypertensive treatment. Recently, activation of the complement alternative pathway (AP) has been reported t...

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Veröffentlicht in:Nephrology, dialysis, transplantation dialysis, transplantation, 2021-07, Vol.36 (7), p.1222-1233
Hauptverfasser: Zhang, Ying, Yang, Chaona, Zhou, Xinjin, Hu, Ruimin, Quan, Songxia, Zhou, Yali, Li, Yuan, Xing, Guolan
Format: Artikel
Sprache:eng
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