MnTE‐2‐PyP disrupts Staphylococcus aureus biofilms in a novel fracture model

Biofilm‐associated infections in orthopedic surgery lead to worse clinical outcomes and greater morbidity and mortality. The scope of the problem encompasses infected total joints, internally fixed fractures, and implanted devices. Diagnosis is difficult. Cultures are often negative, and antibiotic...

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Veröffentlicht in:	Journal of orthopaedic research 2021-11, Vol.39 (11), p.2439-2445
Hauptverfasser:	Lindsay, Sarah E., Lindsay, Hunter G., Kallet, Julia, Weaver, Michael R., Curran‐Everett, Douglas, Crapo, James D., Regan, Elizabeth A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Bacterial Agents - pharmacology Anti-Bacterial Agents - therapeutic use Biofilms bone infection Metalloporphyrins - pharmacology Metalloporphyrins - therapeutic use Mice Reactive Oxygen Species Staphylococcus aureus therapeutics treatment
Online-Zugang:	Volltext
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