BMP9 and BMP10 Act Directly on Vascular Smooth Muscle Cells for Generation and Maintenance of the Contractile State

Vascular smooth muscle cells (VSMCs) show a remarkable phenotypic plasticity, allowing acquisition of contractile or synthetic states, but critical information is missing about the physiologic signals, promoting formation, and maintenance of contractile VSMCs in vivo. BMP9 and BMP10 (bone morphogene...

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Veröffentlicht in:	Circulation (New York, N.Y.) N.Y.), 2021-04, Vol.143 (14), p.1394-1410
Hauptverfasser:	Wang, Lei, Rice, Megan, Swist, Sandra, Kubin, Thomas, Wu, Fan, Wang, Shengpeng, Kraut, Simone, Weissmann, Norbert, Böttger, Thomas, Wheeler, Matthew, Schneider, Andre, Braun, Thomas
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bone Morphogenetic Proteins - metabolism Cell Differentiation Growth Differentiation Factor 2 - metabolism Humans Mice Muscle, Smooth, Vascular - physiology Myocardial Contraction - physiology
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