Chemopreventive effects of vitamin D3 and its analogue, paricalcitol, in combination with 5-fluorouracil against colorectal cancer: The role of calcium signalling molecules

Although vitamin D (VD) is chemoprotective and enhances 5-fluorouracil (5-FU) cytotoxicity against colorectal cancer (CRC), little is known about its potential calcium (Ca2+)-mediated anti-tumorigenic actions. Therefore, this study compared between VD and its non-calcaemic analogue, Paricalcitol (Pc...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Biochimica et biophysica acta. Molecular basis of disease 2021-03, Vol.1867 (3), p.166040-166040, Article 166040
Hauptverfasser:	Aslam, Akhmed, Ahmad, Jawwad, Baghdadi, Mohammed A., Idris, Shakir, Almaimani, Riyad, Alsaegh, Aiman, Alhadrami, Mai, Refaat, Bassem
Format:	Artikel
Sprache:	eng
Schlagworte:	Bcl-2-associated X protein Calcium Calmodulin Calmodulin-dependent kinase II Cytochrome C Vitamin D receptor
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!