Design and characterization of a novel pH-sensitive biocompatible and multifunctional nanocarrier for in vitro paclitaxel release

Breast cancer is one of the main reasons of women's mortality. A novel ternary combination of ZnAl-layered double hydroxides (LDH), cobalt ferrite (CoFe2O4) and N-graphene quantum dots (N-GQDs) proposes a pH-sensitive multifunctional nanocomposite that can improve therapeutic features of each c...

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Veröffentlicht in:	Materials Science & Engineering C 2021-02, Vol.119, p.111627-111627, Article 111627
Hauptverfasser:	Vajedi, Fahimeh Sadat, Dehghani, Hossein, Zarrabi, Ali
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic drugs Antitumor agents Biocompatibility Biomedical materials Blood coagulation Breast cancer Cell aggregation Cell viability Chemical compounds Chemotherapy Cobalt Cobalt ferrite Cobalt ferrites Complement activation Complement component C3 Complement component C4 Controlled release Cytotoxicity Drug delivery Drug Delivery Systems Drug development Drug Liberation Electrochemistry Erythrocytes Female Graphene Humans Hydrogen-Ion Concentration Hydroxides Layered double hydroxide Materials science Multifunctional smart nanocarriers N-graphene quantum dots Nanocomposites Paclitaxel Paclitaxel - pharmacology Paclitaxel delivery pH effects pH-sensitive Pharmacology Polyethylene glycol Prothrombin Quantum dots Sustained release Thromboplastin Toxicity Voltammetry
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