Triggering G‐Quadruplex Conformation Switching with [7]Helicenes

The dynamic interplay between two types of chiral structures; fully conjugated racemic hetero[7]helicenes and DNA strands prone to fold into G‐quadruplex structures is described. Both the [7]helicenes and the G‐quadruplex DNA structures exist in more than one conformation in solution. We show that t...

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Veröffentlicht in:	Chemistry : a European journal 2021-04, Vol.27 (19), p.6064-6069
Hauptverfasser:	Lousen, Bodil, Pedersen, Stephan K., Răsădean, Dora M., Pantoş, G. Dan, Pittelkow, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemistry chirality Circular Dichroism Conformation conformational analysis Deoxyribonucleic acid DNA Enantiomers G-Quadruplexes helical structures Hybrid structures Ligands Nucleic Acid Conformation Polycyclic Compounds Racemization Switching Telomere
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