Design of a dendrimer with a matrix metalloproteinase-responsive fluorescence probe and a tumor-homing peptide for metastatic tumor cell imaging in the lymph node

[Display omitted] •A dendrimer imaging agent for metastatic tumor cells in the lymph node was designed.•A carboxy-terminal dendrimer was used as a carrier for delivery to lymph nodes.•A matrix metaloproteinase-2 (MMP-2) responsive fluorescence probe was conjugated.•Modification of a tumor homing pep...

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Veröffentlicht in:	Bioorganic & medicinal chemistry letters 2021-02, Vol.33, p.127726-127726, Article 127726
Hauptverfasser:	Nagai, Kento, Sato, Tatsumi, Kojima, Chie
Format:	Artikel
Sprache:	eng
Schlagworte:	Dendrimer Matrix metalloproteinase Metastasis Tumor imaging Tumor-homing peptide
Online-Zugang:	Volltext
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