New computational model for miRNA-mediated repression reveals novel regulatory roles of miRNA bindings inside the coding region

Abstract Motivation MicroRNAs (miRNAs) are short (∼24nt), non-coding RNAs, which downregulate gene expression in many species and physiological processes. Many details regarding the mechanism which governs miRNA-mediated repression continue to elude researchers. Results We elucidate the interplay be...

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Veröffentlicht in:	Bioinformatics (Oxford, England) England), 2021-04, Vol.36 (22-23), p.5398-5404
Hauptverfasser:	Bergman, Shaked, Diament, Alon, Tuller, Tamir
Format:	Artikel
Sprache:	eng
Schlagworte:	3' Untranslated regions Availability Binding sites Bioinformatics Gene expression MicroRNAs miRNA Open reading frames Regularization Regulatory sequences Ribosomes
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