Synthesis, design, and assessment of novel morpholine-derived Mannich bases as multifunctional agents for the potential enzyme inhibitory properties including docking study

[Display omitted] •New morpholine derived Schiff bases substituents.•Results of the inhibition activity against AChE, BChE, and GST.•Docking studies of Schiff base 4a-h with three enzymes were performed.•Some new Schiff bases demonstrated remarkable inhibition activity against the enzymes. The synth...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Bioorganic chemistry 2021-02, Vol.107, p.104524-104524, Article 104524
Hauptverfasser:	Boy, Songül, Türkan, Fikret, Beytur, Murat, Aras, Abdülmelik, Akyıldırım, Onur, Karaman, Halide Sedef, Yüksek, Haydar
Format:	Artikel
Sprache:	eng
Schlagworte:	Docking Enzyme inhibitory Mannich bases Morpholine Schiff base
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!