IGF1 does not overcome sexual dimorphism of body and muscle size in Mstn−/− mice

Insulin-like growth factor-1 (IGF1) is crucial for regulating post-natal growth and, along with myostatin (MSTN), regulates muscle size. Here, we sought to clarify the roles of these two genes in regulating sexually dimorphic growth of body and muscle mass. In the first study, we established that Ig...

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Veröffentlicht in:Journal of endocrinology 2021-02, Vol.248 (2), p.207-220
Hauptverfasser: Paul, Ryan, Whiteman, Kim, Falconer, Shelley J, Oldham, Jenny M, Jeanplong, Ferenc, Matthews, Kenneth G, Smith, Heather K, Thomas, Mark, Watson, Trevor, McMahon, Christopher D
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Sprache:eng
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