Immunological and biochemical response of older adults with urinary tract infection to uropathogenic Esherichia coli virulence factors

Descriptive study in which 24 urine samples from older adults with urinary tract infection (UTI), from nursing homes, were evaluated; in order to identify differences in the immune and biochemical response from older adults with UTI by Escherichia coli (E. coli) to major virulence factors in the pat...

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Veröffentlicht in:Revista peruana de medicina experimental y salud pública 2020-12, Vol.37 (3), p.527-531
Hauptverfasser: Gonzales-Rodriguez, Arturo Octavio, Infante Varillas, Stefany Fiorella, Barrón Pastor, Heli Jaime, Llimpe Mitma, Yesica, Huerta Canales, Doris, Wong Chero, Paolo Alberto, Gutierrez, César, Suarez Cunza, Silvia
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container_title Revista peruana de medicina experimental y salud pública
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creator Gonzales-Rodriguez, Arturo Octavio
Infante Varillas, Stefany Fiorella
Barrón Pastor, Heli Jaime
Llimpe Mitma, Yesica
Huerta Canales, Doris
Wong Chero, Paolo Alberto
Gutierrez, César
Suarez Cunza, Silvia
description Descriptive study in which 24 urine samples from older adults with urinary tract infection (UTI), from nursing homes, were evaluated; in order to identify differences in the immune and biochemical response from older adults with UTI by Escherichia coli (E. coli) to major virulence factors in the pathogenesis of UTI. Iron concentration, TNF-α, IL-1β and antioxidant capacity in urine were determined. A relation was found between, an increase in iron and red blood cell concentration in urine, and the presence of the pap GII gene found in E. coli. It is concluded that older adults, with UTIs by E. coli with the gene pap GII, have increased tissue damage.
doi_str_mv 10.17843/rpmesp.2020.373.4918
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subjects Aged
Escherichia coli Infections - immunology
Escherichia coli Infections - microbiology
Humans
Immunity
Urinary Tract Infections - immunology
Urinary Tract Infections - microbiology
Uropathogenic Escherichia coli - genetics
Uropathogenic Escherichia coli - pathogenicity
Virulence Factors
title Immunological and biochemical response of older adults with urinary tract infection to uropathogenic Esherichia coli virulence factors
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