IRE1 and CaMKKβ pathways to reveal the mechanism involved in microcystin-LR-induced autophagy in mouse ovarian cells

Microcystin-LR (MC-LR) is an emerging water pollutant produced by blooming cyanobacteria. It could be absorbed into human body via contaminated food and drinking water causing severe reproductive toxicity. Previous studies showed that MC-LR could regulate autophagy by inducing endoplasmic reticulum...

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Veröffentlicht in:	Food and chemical toxicology 2021-01, Vol.147, p.111911-111911, Article 111911
Hauptverfasser:	Ma, Ya, Liu, Haohao, Du, Xingde, Petlulu, Pavankumar, Chen, Xinghai, Wang, Rui, Zhang, Shiyu, Tian, Zhihui, Shi, Linjia, Guo, Hongxiang, Zhang, Huizhen
Format:	Artikel
Sprache:	eng
Schlagworte:	autophagy Ca2+/calmodulin-dependent protein kinase kinase inositol-requiring enzyme 1 microcystin-LR reproductive toxicity
Online-Zugang:	Volltext
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